Invitrogen

AMD1 Polyclonal Antibody

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AMD1 Antibody in Western Blot (WB) — Western Blot using AMD1 Polyclonal Antibody (Product # PA5-31540). Sample (30 µg of whole cell lysate). Lane A: A431. 10% SDS PAGE. AMD1 Polyclonal Antibody (Product # PA5-31540) diluted at 1:1,000.

Product Details

PA5-31540

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein fragment corresponding to a region within amino acids 44 and 226 of Human AMD1 View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7, with 1% BSA, 20% glycerol
Contains	0.01% thimerosal
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2549013

Product Specific Information

Recommended positive controls: 293T, A431, Jurkat, Raji.

Predicted reactivity: Mouse (99%), Rat (97%), Zebrafish (80%), Xenopus laevis (85%), Chicken (92%), Bovine (99%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

Biochimica et biophysica acta. Molecular basis of disease

Lane DJR,Bae DH,Siafakas AR,Suryo Rahmanto Y,Al-Akra L,Jansson PJ,Casero RA,Richardson DR

PA5-31540 was used in Western Blotting to investigate the metabolic link between iron and polyamine metabolism.

Sat Sep 01 00:00:00 EDT 2018

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

Biochimica et biophysica acta. Molecular basis of disease

Lane DJR,Bae DH,Siafakas AR,Suryo Rahmanto Y,Al-Akra L,Jansson PJ,Casero RA,Richardson DR

PA5-31540 was used in Western Blotting to investigate the metabolic link between iron and polyamine metabolism.

Sat Sep 01 00:00:00 EDT 2018

Bioinformatics

Protein Aliases: AdoMetDC; DKFZp313L1234; FLJ26964; S-adenosylmethionine decarboxylase 1; S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain; S-adenosylmethionine decarboxylase proenzyme

Gene Aliases: ADOMETDC; AMD; AMD1; SAMDC

UniProt ID: (Human) P17707

Entrez Gene ID: (Human) 262

Molecular Function: decarboxylase

Function(s)

S-adenosylmethioninamine biosynthetic process polyamine metabolic process spermine biosynthetic process spermidine biosynthetic process S-adenosylmethionine metabolic process

Process(es)

adenosylmethionine decarboxylase activity putrescine binding

AMD1 Polyclonal Antibody

Product Details

PA5-31540

Western Blot (WB)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

RRID

Product Specific Information

Target Information

Bioinformatics

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