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Product Details
PA5-114845
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Non-human primate |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human AMELX(Accession Q99217), corresponding to amino acid residues Q92-P111. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2899481 |
Target Information
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); amelogenin X chromosome; Amelogenin, X isoform; enamel matrix protein; Leucine-rich amelogenin peptide; LRAP
Gene Aliases: AI1E; AIH1; ALGN; Amel; AMELX; AMG; AMGL; AMGX; LRAP; M100888; Rgsc888
UniProt ID: (Human) Q99217, (Mouse) P63277
Entrez Gene ID: (Human) 265, (Mouse) 11704
osteoblast differentiation
epithelial to mesenchymal transition
chondrocyte differentiation
cell adhesion
signal transduction
cell proliferation
biomineral tissue development
positive regulation of collagen biosynthetic process
tooth mineralization
odontogenesis of dentin-containing tooth
ion homeostasis
enamel mineralization
positive regulation of tooth mineralization
multicellular organism development
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