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Product Details
PA5-118945
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.2-2 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
5-20 µg/mL | - |
Immunocytochemistry (ICC/IF) |
5-20 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein Amelogenin, X-Linked. The antigen corresponds to amino acid range 49-187 of the target protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
500 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.05% ProClin 300 |
Storage conditions |
-20°C |
RRID |
AB_2903445 |
Target Information
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); Amelogenin, X isoform
Gene Aliases: AI1E; AIH1; ALGN; AMELX; AMG; AMGL; AMGX
UniProt ID: (Human) Q99217
Entrez Gene ID: (Human) 265
osteoblast differentiation
epithelial to mesenchymal transition
chondrocyte differentiation
cell adhesion
signal transduction
cell proliferation
biomineral tissue development
positive regulation of collagen biosynthetic process
tooth mineralization
odontogenesis of dentin-containing tooth
ion homeostasis
enamel mineralization
positive regulation of tooth mineralization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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