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Product Details
PA5-31286
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Published species |
Not Applicable |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 1 and 191 of Human AMELX |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2548760 |
Product Specific Information
Recommended positive controls: Jurkat, NIH-3T3.
Predicted reactivity: Mouse (81%), Rat (81%), Pig (82%), Rhesus Monkey (98%), Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: amelogenesis imperfecta 1; amelogenin (amelogenesis imperfecta 1, X-linked); amelogenin (X chromosome, amelogenesis imperfecta 1); amelogenin X chromosome; Amelogenin, X isoform; enamel matrix protein; Leucine-rich amelogenin peptide; LRAP
Gene Aliases: AI1E; AIH1; ALGN; Amel; AMELX; AMG; AMGL; AMGX; LRAP; M100888; Rgsc888
UniProt ID: (Human) Q99217, (Mouse) P63277
Entrez Gene ID: (Human) 265, (Mouse) 11704
osteoblast differentiation
epithelial to mesenchymal transition
chondrocyte differentiation
cell adhesion
signal transduction
cell proliferation
biomineral tissue development
positive regulation of collagen biosynthetic process
tooth mineralization
odontogenesis of dentin-containing tooth
ion homeostasis
enamel mineralization
positive regulation of tooth mineralization
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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