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Proteintech
AMFR Polyclonal Antibody
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Product Details
16675-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMFR Fusion Protein Ag10178 (301-643 aa encoded by BC069197)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LFHEVQRRI RRHKNYLRVV GNMEARFAVA TPEELAVNND DCAICWDSMQ AARKLPCGHL FHNSCLRSWL EQDTSCPTCR MSLNIADNNR VREEHQGENL DENLVPVAAA EGRPRLNQHN HFFHFDGSRI ASWLPSFSVE VMHTTNILGI TQASNSQLNA MAHQIQEMFP QVPYHLVLQD LQLTRSVEIT TDNILEGRIQ VPFPTQRSDS IRPALNSPVE RPSSDQEEGE TSAQTERVPL DLSPRLEETL DFGEVEVEPS EVEDFEARGS RFSKSADERQ RMLVQRKDEL LQQARKRFLN KSSEDDAASE SFLPSEGASS DPVTLRRRML AAAAERRLQK QQTS (301-643 aa encoded by B C069197)
Target Information
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AMF receptor; Autocrine motility factor receptor; autocrine motility factor receptor, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase AMFR; gp78; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR
Gene Aliases: AMFR; GP78; RNF45
UniProt ID: (Human) Q9UKV5, (Mouse) Q9R049
Entrez Gene ID: (Human) 267, (Rat) 361367, (Mouse) 23802
ubiquitin-protein transferase activity
receptor activity
protein binding
zinc ion binding
ligase activity
protein binding, bridging
ubiquitin-ubiquitin ligase activity
chaperone binding
ubiquitin protein ligase activity
ubiquitin protein ligase activity involved in ERAD pathway
BAT3 complex binding
ubiquitin-specific protease binding
molecular_function
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein modifying enzyme
protein polyubiquitination
ubiquitin-dependent protein catabolic process
movement of cell or subcellular component
signal transduction
aging
learning or memory
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
positive regulation of protein binding
ERAD pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
protein oligomerization
protein autoubiquitination
protein K48-linked ubiquitination
cellular process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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