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AMH Antibody (PA5-119826) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded rat testis tissue using AMH Polyclonal Antibody (Product # PA5-119826). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the AMH antibody at a dilution of 1:100 ... View More
Product Details
PA5-119826
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human AMH aa 50-230
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913398
Product Specific Information
Positive Control: 293T cell lysate, A431 cell lysate, HepG2 cell lysate, Hela cell lysate, mouse testis tissue lysate, rat testis tissue lysate, 293T, rat testis tissue.
Subcellular Location: Secreted.
Target Information
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMH; Anti - Mullerian hormone (Mulerian inhibiting substance); Anti-Muellerian hormone; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
Gene Aliases: AMH; MIF; MIS
UniProt ID: (Human) P03971, (Rat) P49000, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Rat) 25378, (Mouse) 11705
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
cell-cell signaling
gonadal mesoderm development
aging
positive regulation of gene expression
response to organic cyclic compound
response to drug
positive regulation of NF-kappaB transcription factor activity
negative regulation of ovarian follicle development
sex determination
sex differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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