Product References
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Evidence-based complementary and alternative medicine : eCAM
Zhang J,Zhang Q,Chen X,Liu Y,Xue J,Dahan A,Zhang H,Chai Y
Thu Oct 01 00:00:00 EDT 2020
Restoring mitochondrial biogenesis with metformin attenuates β-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype via inhibition of PDK4/oxidative stress-mediated apoptosis.
Molecular and cellular endocrinology
Ma WQ,Sun XJ,Wang Y,Zhu Y,Han XQ,Liu NF
Sat Jan 05 00:00:00 EST 2019
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cheng B,Lu J,Li T,Meng Z,Liu M,Sun M,Guan S
Sat Dec 01 00:00:00 EST 2018
9-O-benzoyl-substituted berberine exerts a triglyceride-lowering effect through AMPK signaling pathway in human hepatoma HepG2 cells.
Environmental toxicology and pharmacology
Cao S,Yu S,Cheng L,Yan J,Zhu Y,Deng Y,Qiu F,Kang N
Sat Dec 01 00:00:00 EST 2018
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Gu S,Hua H,Guo X,Jia Z,Zhang Y,Maslov LN,Zhang X,Ma H
Mon Nov 26 00:00:00 EST 2018
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Medical science monitor : international medical journal of experimental and clinical research
Gao J,Xiong R,Xiong D,Zhao W,Zhang S,Yin T,Zhang X,Jiang G,Yin Z
Mon Nov 26 00:00:00 EST 2018
Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma.
Cancer medicine
Dai J,Huang Q,Niu K,Wang B,Li Y,Dai C,Chen Z,Tao K,Dai J
Thu Nov 01 00:00:00 EDT 2018
Effect of Omega-3 Fatty Acid on STAMP2 Expression in the Heart and Kidney of 5/6 Nephrectomy Rat Model.
Marine drugs
Lee HW,Lee SM,Lee MH,Son YK,Kim SE,An WS
Tue Oct 23 00:00:00 EDT 2018
MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.
Molecular and cellular endocrinology
Zeng N,Huang R,Li N,Jiang H,Li R,Wang F,Chen W,Xia M,Wang Q
Mon Oct 15 00:00:00 EDT 2018
Panobinostat and Nelfinavir Inhibit Renal Cancer Growth by Inducing Endoplasmic Reticulum Stress.
Anticancer research
Okubo K,Isono M,Asano T,Sato A
Mon Oct 01 00:00:00 EDT 2018
Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice.
Prostaglandins, leukotrienes, and essential fatty acids
Guo XF,Sinclair AJ,Kaur G,Li D
Sat Sep 01 00:00:00 EDT 2018
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Oxidative medicine and cellular longevity
Dun Y,Liu S,Zhang W,Xie M,Qiu L
Fri Aug 17 00:00:00 EDT 2018
Delanzomib Interacts with Ritonavir Synergistically to Cause Endoplasmic Reticulum Stress in Renal Cancer Cells.
Anticancer research
Isono M,Sato A,Asano T,Okubo K,Asano T
Fri Jun 01 00:00:00 EDT 2018
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Cell death & disease
Luo X,Wang D,Zhu X,Wang G,You Y,Ning Z,Li Y,Jin S,Huang Y,Hu Y,Chen T,Meng Y,Li X
Tue May 01 00:00:00 EDT 2018
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Pharmacological research
Yan J,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Sun H
Sun Apr 01 00:00:00 EDT 2018
Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats.
Brain research
Cao M,Fang J,Wang X,Wang Y,Duan K,Ye F,Ouyang W,Tong J
Sun Apr 01 00:00:00 EDT 2018
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
Biochemical and biophysical research communications
Liu JQ,Zhang L,Yao J,Yao S,Yuan T
Sun Mar 04 00:00:00 EST 2018
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
Cell death & disease
Li CF,Sun JX,Gao Y,Shi F,Pan YK,Wang YC,Sun XQ
Fri Feb 02 00:00:00 EST 2018
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Biochemical and biophysical research communications
Cheng G,Li B,Sun X,Cao Z,Zhang G,Zhao Z,Zhao Y,Yu Q,Liu W
Mon Jan 29 00:00:00 EST 2018
Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway.
Toxicology and applied pharmacology
Zhao Y,Shi X,Ding C,Feng D,Li Y,Hu Y,Wang L,Gao D,Tian X,Yao J
Mon Jan 15 00:00:00 EST 2018
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng L,Yin L,Xu L,Qi Y,Li H,Xu Y,Han X,Liu K,Peng J
Mon Jan 01 00:00:00 EST 2018
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Cell communication and signaling : CCS
Li M,Jin C,Xu M,Zhou L,Li D,Yin Y
Sat Dec 16 00:00:00 EST 2017
AMP-activated protein kinase and cAMP response element-binding protein activity are associated with distinct postoperative behavioral changes in rats.
Journal of anesthesia
Li D,Ye F,Ouyang W,Wang Y
Fri Dec 01 00:00:00 EST 2017
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Molecules (Basel, Switzerland)
Song L,Wang Z,Wang Y,Guo D,Yang J,Chen L,Tan N
Sat Nov 11 00:00:00 EST 2017
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Redox biology
Luo X,Luo X,Zhu X,Wang G,Ning Z,Li Y,Ma X,Yang R,Jin S,Huang Y,Meng Y,Li X
Sun Oct 01 00:00:00 EDT 2017
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
PloS one
Ran G,Ying L,Li L,Yan Q,Yi W,Ying C,Wu H,Ye X
Fri Sep 22 00:00:00 EDT 2017
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
Oncotarget
La X,Zhang L,Li Z,Yang P,Wang Y
Tue Mar 28 00:00:00 EDT 2017
Chronic metformin treatment facilitates seizure termination.
Biochemical and biophysical research communications
Yang Y,Zhu B,Zheng F,Li Y,Zhang Y,Hu Y,Wang X
Sat Mar 04 00:00:00 EST 2017
Chronic metformin treatment facilitates seizure termination.
Biochemical and biophysical research communications
Yang Y,Zhu B,Zheng F,Li Y,Zhang Y,Hu Y,Wang X
Sat Mar 04 00:00:00 EST 2017
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Scientific reports
Zhou S,Lu W,Chen L,Ge Q,Chen D,Xu Z,Shi D,Dai J,Li J,Ju H,Cao Y,Qin J,Chen S,Teng H,Jiang Q
Wed Feb 22 00:00:00 EST 2017
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Scientific reports
Zhou S,Lu W,Chen L,Ge Q,Chen D,Xu Z,Shi D,Dai J,Li J,Ju H,Cao Y,Qin J,Chen S,Teng H,Jiang Q
Wed Feb 22 00:00:00 EST 2017
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Free radical biology & medicine
Dong K,Wu M,Liu X,Huang Y,Zhang D,Wang Y,Yan LJ,Shi D
Thu Dec 01 00:00:00 EST 2016
Activation of AMPK α2 inhibits airway smooth muscle cells proliferation.
European journal of pharmacology
Liu L,Pan Y,Song Y,Su X,Ke R,Yang L,Gao L,Li M
Tue Nov 15 00:00:00 EST 2016
The Effect of Hippocampal Cognitive Impairment and XIAP on Glucose and Lipids Metabolism in Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Xia C,Zhu L,Shao W,Mi S,Du S,Ye L,Liu M,Pang Y,Nong L,Jiang C,Zhao H,Qi G
Tue Nov 08 00:00:00 EST 2016
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
International journal of clinical and experimental pathology
Ye X,Zhang Y,He B,Meng Y,Li Y,Gao Y
Mon Oct 31 00:00:00 EDT 2016
Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats.
Scientific reports
Li L,Xiao L,Hou Y,He Q,Zhu J,Li Y,Wu J,Zhao J,Yu S,Zhao Y
Mon Jul 25 00:00:00 EDT 2016
Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway.
International journal of molecular sciences
Ke R,Liu L,Zhu Y,Li S,Xie X,Li F,Song Y,Yang L,Gao L,Li M
Tue May 31 00:00:00 EDT 2016
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Cell & bioscience
Liu J,Wu J,Sun A,Sun Y,Yu X,Liu N,Dong S,Yang F,Zhang L,Zhong X,Xu C,Lu F,Zhang W
Wed May 25 00:00:00 EDT 2016
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Cell & bioscience
Liu J,Wu J,Sun A,Sun Y,Yu X,Liu N,Dong S,Yang F,Zhang L,Zhong X,Xu C,Lu F,Zhang W
Wed May 25 00:00:00 EDT 2016
Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis.
Oncotarget
Liu Q,Yuan W,Tong D,Liu G,Lan W,Zhang D,Xiao H,Zhang Y,Huang Z,Yang J,Zhang J,Jiang J
Tue May 10 00:00:00 EDT 2016
AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth.
Protein & cell
Zhu K,Chen X,Liu J,Ye H,Zhu L,Wu JY
Fri Feb 01 00:00:00 EST 2013