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Proteintech
ANK3 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-27980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MGLLDRLDDS PDQCRDSITS YLKGEAGKFE ANGSHTEITP EAKTKSYFPE SQNDVGKQST KETLKPKIHG SGHVEEPASP LAAYQKSLEE TSKLIIEETK PCVPVSMKKM SRTSPADGKP RLSLHEEEGS SGSEQKQGEG FKVKTKKEIR HVEKKSHS
Target Information
Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANK-3; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); Ankyrin-3; Ankyrin-G; brain-specific ankyrin-G; unnamed protein product
Gene Aliases: 2900054D09Rik; AI314020; ANK-3; ANK3; AnkG; Ankyrin-3; ANKYRIN-G; MRT37
UniProt ID: (Human) Q12955, (Rat) O70511, (Mouse) G5E8K5
Entrez Gene ID: (Human) 288, (Rat) 361833, (Mouse) 11735
mitotic cytokinesis
plasma membrane organization
cytoskeleton organization
signal transduction
axonogenesis
neuromuscular junction development
positive regulation of gene expression
positive regulation of cell communication by electrical coupling
positive regulation of sodium ion transport
magnesium ion homeostasis
neuronal action potential
positive regulation of homotypic cell-cell adhesion
Golgi to plasma membrane protein transport
regulation of potassium ion transport
establishment of protein localization
positive regulation of membrane potential
Golgi vesicle transport
cellular response to magnesium ion
membrane assembly
protein localization to plasma membrane
maintenance of protein location in plasma membrane
positive regulation of protein targeting to membrane
protein localization to axon
positive regulation of membrane depolarization during cardiac muscle cell action potential
negative regulation of delayed rectifier potassium channel activity
axon guidance
synapse organization
protein targeting to plasma membrane
positive regulation of sodium ion transmembrane transporter activity
positive regulation of cation channel activity
positive regulation of action potential
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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