Immunogen sequence: ACYVYRKQKKK MENESATEGE DSAMTDMPPT EEVTDIVEMR EENE
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 98%.
ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
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Protein Aliases: ANK; Ankylosis; ankylosis, progressive homolog; CCAL2; CMDJ; CPPDD; FLJ27166; HANK; MANK; Progressive ankylosis protein homolog; progressive homolog (mouse)
Gene Aliases: ANK; ANKH; CCAL2; CMDJ; CPPDD; HANK; KIAA1581; MANK; UNQ241/PRO274
UniProt ID: (Human) Q9HCJ1
Entrez Gene ID: (Human) 56172