Recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ankyrin repeat domain-containing protein 6; diego homolog; Diversin
Gene Aliases: ANKRD6; KIAA0957
UniProt ID: (Human) Q5JUJ4
Entrez Gene ID: (Human) 22881