AP-1 complex subunit beta-1 is a subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
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Protein Aliases: adapter-related protein complex 1 subunit beta-1; Adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; adaptor-related protein complex 1 beta 1 subunit; Adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; adaptor-related protein complex AP-1, beta 1 subunit; ADTB1; AP 1 complex subunit beta 1; AP-1 complex subunit beta-1; AP105A; AP1B1; BAM22; Beta 1 adaptin; Beta adaptin 1; Beta-1-adaptin; Beta-adaptin 1; beta-prime adaptin; beta-prime-adaptin; beta1-adaptin; CLAPB2; Clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit; Mutant line 1660; plasma membrane adaptor HA2/AP2 adaptor beta subunit
Gene Aliases: ADTB1; AP105A; AP1B1; b2b1660Clo; BAM22; CLAPB2
Molecular Function: membrane traffic protein