This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
AP1S1 is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle.
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Protein Aliases: adapter-related protein complex 1 sigma-1A subunit; adapter-related protein complex 1 subunit sigma-1A; adaptor protein complex AP-1 sigma-1A subunit; Adaptor protein complex AP-1 subunit sigma-1A; Adaptor-related protein complex 1 subunit sigma-1A; adaptor-related protein complex AP-1, sigma 1; AP-1 complex subunit sigma-1A; Clathrin assembly protein complex 1 sigma-1A small chain; Clathrin coat assembly protein AP19; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; Sigma 1a subunit of AP-1 clathrin; Sigma-adaptin 1A; Sigma1A-adaptin; WUGSC:H_DJ0747G18.2
Gene Aliases: AP19; Ap1s1
UniProt ID: (Mouse) P61967
Entrez Gene ID: (Mouse) 11769
Molecular Function: vesicle coat protein