Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
ELISA (ELISA) |
1:5,000-1:20,000 | - |
Immunoprecipitation (IP) |
1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Dog, Chicken, Chimpanzee, Human, Mouse, Non-human primate, Rat |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
synthetic peptide AVSKGDGMRGLAC, corresponding to amino acids 3 - 14 of Human AP2 alpha. |
Conjugate |
Unconjugated |
Form |
Liquid |
Purification |
Antigen affinity chromatography |
Storage buffer |
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
Contains |
0.01% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2287244 |
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activating enhancer-binding protein 2 alpha; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2; AP-2 transcription factor; AP2-alpha; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); Transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor AP2
Gene Aliases: AP-2; Ap-2 (a); AP-2alpha; Ap2; AP2alpha; AP2TF; BOFS; Tcfap2a; TFAP2; TFAP2A
UniProt ID: (Human) P05549, (Mouse) P34056
Entrez Gene ID: (Dog) 488213, (Human) 7020, (Chicken) 395982, (Mouse) 21418, (Rat) 306862
Molecular Function:
general transcription factor
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