The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: activating enhancer binding protein 2 beta; activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2 beta; Activating enhancer-binding protein 2-alpha; Activating enhancer-binding protein 2-beta; Activator protein 2; AP-2; AP-2 transcription factor; AP2-alpha; AP2-beta; FLJ51761; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2 beta (activating enhancer binding protein 2 beta); Transcription factor AP-2-alpha; Transcription factor AP-2-beta
Gene Aliases: AI606113; AP-2; Ap-2 (a); AP-2(beta); AP-2alpha; AP-2B; Ap2; AP2-B; AP2alpha; AP2TF; BOFS; E130018K07Rik; Tcfap2a; Tcfap2b; TFAP2; TFAP2A; TFAP2B
Molecular Function: transcription factor