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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 232 and 423 of Human AP2 beta|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30189 targets AP2 beta in WB applications and shows reactivity with Human samples.
The PA5-30189 immunogen is recombinant protein fragment corresponding to a region within amino acids 232 and 423 of Human AP2 beta.
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
activating enhancer binding protein 2 beta; activating enhancer-binding protein 2-beta; AP-2B; AP2-B; AP2-beta; transcription factor AP-2 beta (activating enhancer binding protein 2 beta); transcription factor AP-2-beta
AP-2B; AP2-B; TFAP2B