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Proteintech
AP2A1 Polyclonal Antibody
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Product Details
30030-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LKRKKGPGAG SALDDGRRDP SSNDINGGME PTPSTVSTPS PSADLLGLRA APPPAAPPAS AGAGNLLVDV FDGPAAQPSL GPTPEEAFLS PGPEDIGPPI PEADELLNK
Target Information
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 100 kDa coated vesicle protein A; adapter-related protein complex 2 alpha-1 subunit; adapter-related protein complex 2 subunit alpha-1; adaptin, alpha A; Adaptor protein complex AP-2 subunit alpha-1; adaptor protein complex AP-2, alpha 1 subunit; adaptor related protein complex 2 alpha 1 subunit; Adaptor-related protein complex 2 subunit alpha-1; adaptor-related protein complex AP-2, alpha 1 subunit; ADTAA; Alpha-adaptin A; Alpha1-adaptin; AP-2 alpha subunit; AP-2 complex subunit alpha-1; CLAPA1; Clathrin assembly protein complex 2 alpha-A large chain; clathrin-associated/assembly/adaptor protein, large, alpha 1; Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit; unnamed protein product
Gene Aliases: ADTAA; AP2-ALPHA; AP2A1; CLAPA1
UniProt ID: (Human) O95782, (Mouse) P17426
Entrez Gene ID: (Human) 160, (Rat) 308578, (Mouse) 11771
intracellular protein transport
Golgi to endosome transport
endocytosis
positive regulation of neuron projection development
protein transport
vesicle-mediated transport
positive regulation of receptor-mediated endocytosis
synaptic vesicle endocytosis
clathrin-mediated endocytosis
postsynaptic neurotransmitter receptor internalization
negative regulation of hyaluronan biosynthetic process
biological_process
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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