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Proteintech
AP3B1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
13384-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AP3B1 Fusion Protein Ag4225 (763-1094 aa encoded by BC038444)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KTSDSSNDE SSSIEDSSSD SESESEPESE SESRRVTKEK EKKTKQDRTP LTKDVSLLDL DDFNPVSTPV ALPTPALSPS LMADLEGLHL STSSSVISVS TPAFVPTKTH VLLHRMSGKG LAAHYFFPRQ PCIFGDKMVS IQITLNNTTD RKIENIHIGE KKLPIGMKMH VFNPIDSLEP EGSITVSMGI DFCDSTQTAS FQLCTKDDCF NVNIQPPVGE LLLPVAMSEK DFKKEQGVLT GMNETSAVII AAPQNFTPSV IFQKVVNVAN VGAVPSGQDN IHRFAAKTVH SGSLMLVTVE LKEGSTAQLI INTEKTVIGS VLLRELKPVL SQG (763-1094 aa encoded by B C038444)
Target Information
AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adapter-related protein complex 3 subunit beta-1; adaptor protein complex AP-3 beta-1 subunit; adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3 beta 1 subunit; adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex 3, beta 1 subunit; adaptor-related protein complex AP-3 beta 1 subunit; AP-3 complex beta-3A subunit; ap3; beta-3A; beta-3A-adaptin; beta3A-adaptin; clathrin assembly protein complex 3 beta-1 large chain; recombination induced mutation 2; similar to cerebellar degeneration antigen beta-NAP and to the beta-1-adaptin and beta-2-adaptin subunits of clathrin-associated complexes; unnamed protein product
Gene Aliases: ADTB3; ADTB3A; AP-3; beta3A; HPS; HPS2; PE; pearl; rim2
UniProt ID: (Human) O00203, (Mouse) Q9Z1T1
Entrez Gene ID: (Human) 8546, (Rat) 309969, (Mouse) 11774
cell morphogenesis
toll-like receptor signaling pathway
hematopoietic progenitor cell differentiation
antigen processing and presentation of peptide antigen via MHC class II
respiratory system process
protein targeting
protein targeting to lysosome
cellular zinc ion homeostasis
intracellular protein transport
inflammatory response
lysosome organization
spermatogenesis
single fertilization
blood coagulation
anterograde axonal transport
biological_process
gene expression
vesicle-mediated transport
antigen processing and presentation
lung development
granulocyte differentiation
melanosome organization
toll-like receptor 4 signaling pathway
protein localization to cell surface
T-helper 1 cell activation
mRNA transcription from RNA polymerase II promoter
positive regulation of CD4-positive, alpha-beta T cell differentiation
pigmentation
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
anterograde synaptic vesicle transport
synaptic vesicle membrane organization
homeostasis of number of cells
regulation of catalytic activity
positive regulation of NK T cell differentiation
platelet dense granule organization
lung morphogenesis
membrane organization
protein-containing complex assembly
protein localization to mitochondrion
protein localization to membrane
protein localization to plasma membrane
skin epidermis development
zinc ion import into synaptic vesicle
response to Gram-positive bacterium
melanosome assembly
protein localization to phagocytic vesicle
clathrin-coated vesicle cargo loading, AP-3-mediated
neutrophil differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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