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Abnova
AP3B1 Polyclonal Antibody, MaxPab™
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Product Details
H00008546-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AP3B1 (NP_003655.3, 1 a.a. approximately 1094 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSSNSFPYNE QSGGGEATEL GQEATSTISP SGAFGLFSSD LKKNEDLKQM LESNKDSAKL DAMKRIVGMI AKGKNASELF PAVVKNVASK NIEIKKLVYV YLVRYAEEQQ DLALLSISTF QRALKDPNQL IRASALRVLS SIRVPIIVPI MMLAIKEASA DLSPYVRKNA AHAIQKLYSL DPEQKEMLIE VIEKLLKDKS TLVAGSVVMA FEEVCPDRID LIHKNYRKLC NLLVDVEEWG QVVIIHMLTR YARTQFVSPW KEGDELEDNG KNFYESDDDQ KEKTDKKKKP YTMDPDHRLL IRNTKPLLQS RNAAVVMAVA QLYWHISPKS EAGIISKSLV RLLRSNREVQ YIVLQNIATM SIQRKGMFEP YLKSFYVRST DPTMIKTLKL EILTNLANEA NISTLLREFQ TYVKSQDKQF AAATIQTIGR CATNILEVTD TCLNGLVCLL SNRDEIVVAE SVVVIKKLLQ MQPAQHGEII KHMAKLLDSI TVPVARASIL WLIGENCERV PKIAPDVLRK MAKSFTSEDD LVKLQILNLG AKLYLTNSKQ TKLLTQYILN LGKYDQNYDI RDRTRFIRQL IVPNVKSGAL SKYAKKIFLA QKPAPLLESP FKDRDHFQLG TLSHTLNIKA TGYLELSNWP EVAPDPSVRN VEVIELAKEW TPAGKAKQEN SAKKFYSESE EEEDSSDSSS DSESESGSES GEQGESGEEG DSNEDSSEDS SSEQDSESGR ESGLENKRTA KRNSKAKGKS DSEDGEKENE KSKTSDSSND ESSSIEDSSS DSESESEPES ESESRRVTKE KEKKTKQDRT PLTKDVSLLD LDDFNPVSTP VALPTPALSP SLMADLEGLH LSTSSSVISV STPAFVPTKT HVLLHRMSGK GLAAHYFFPR QPCIFGDKMV SIQITLNNTT DRKIENIHIG EKKLPIGMKM HVFNPIDSLE PEGSITVSMG IDFCDSTQTA SFQLCTKDDC FNVNIQPPVG ELLLPVAMSE KDFKKEQGVL TGMNETSAVI IAAPQNFTPS VIFQKVVNVA NVGAVPSGQD NIHRFAAKTV HSGSLMLVTV ELKEGSTAQL IINTEKTVIG SVLLRELKPV LSQG
Target Information
AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3 beta 1 subunit; Adaptor-related protein complex 3 subunit beta-1; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; ap3; beta-3A; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain; unnamed protein product
Gene Aliases: ADTB3; ADTB3A; AP3B1; HPS; HPS2; PE
UniProt ID: (Human) O00203
Entrez Gene ID: (Human) 8546
cell morphogenesis
toll-like receptor signaling pathway
hematopoietic progenitor cell differentiation
respiratory system process
protein targeting
protein targeting to lysosome
cellular zinc ion homeostasis
intracellular protein transport
inflammatory response
lysosome organization
spermatogenesis
single fertilization
blood coagulation
anterograde axonal transport
protein transport
vesicle-mediated transport
antigen processing and presentation
lung development
granulocyte differentiation
melanosome organization
protein localization to cell surface
clathrin-coated vesicle cargo loading, AP-3-mediated
protein modification process
mRNA transcription from RNA polymerase II promoter
pigmentation
positive regulation of transcription from RNA polymerase II promoter
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
anterograde synaptic vesicle transport
homeostasis of number of cells
positive regulation of NK T cell differentiation
platelet dense granule organization
lung morphogenesis
membrane organization
establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
skin epidermis development
melanosome assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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