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Proteintech
AP3B2 Polyclonal Antibody
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Product Details
18331-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AP3B2 Fusion Protein Ag12861 (650-1082 aa encoded by BC093739)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DPSVRNVEV PEWTKCSNRE KRKEKEKPFY SDSEGESGPT ESADSDPESE SESDSKSSSE SGSGESSSES DNEDQDEDEE KGRGSESEQS EEDGKRKTKK KVPERKGEAS SSDEGSDSSS SSSESEMTSE SEEEQLEPAS WSRKTPPSSK SAPATKEISL LDLEDFTPPS VQPVSPPAIV STSLAADLEG LTLTDSTLVP SLLSPVSGVG RQELLHRVAG EGLAVDYTFS RQPFSGDPHM VSVHIHFSNS SDTPIKGLHV GTPKLPAGIS IQEFPEIESL APGESATAVM GINFCDSTQA ANFQLCTQTR QFYVSIQPPV GELMAPVFMS ENEFKKEQGK LMGMNEITEK LMLPDTCRSD HIVVQKVTAT ANLGRVPCGT SDEYRFAGRT LTGGSLVLLT LDARPAGAAQ LTVNSEKMVI GTMLVKDVIQ ALTQ (650-1082 aa encoded by BC093739)
Target Information
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adapter-related protein complex 3 subunit beta-2; adaptor protein complex AP-3 beta-2 subunit; Adaptor protein complex AP-3 subunit beta-2; adaptor related protein complex 3, beta 2 subunit; Adaptor-related protein complex 3 subunit beta-2; adaptor-related protein complex 3, beta 2 subunit; adaptor-related protein complex AP-3, beta 2 subunit; AP-3 complex beta-2 subunit; AP-3 complex subunit beta-2; ap3; Beta-3B-adaptin; beta3B-adaptin; Clathrin a; Clathrin assembly protein complex 3 beta-2 large chain; Neuron-specific vesicle coat protein beta-NAP; Neuronal adaptin-like protein, beta-subunit
Gene Aliases: [b]-NAP; AI549966; AP3B2; AU042881; beta-NAP; beta3B; NAPTB
UniProt ID: (Human) Q13367, (Mouse) Q9JME5
Entrez Gene ID: (Human) 8120, (Mouse) 11775, (Rat) 308777
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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