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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid peptide near the center of human AP3S1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||20 µg/ml|
|Immunohistochemistry (IHC)||2.5 µg/ml|
|Western Blot (WB)||1-2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is mouse kidney tissue lysate.
PA5-21161 can be used with blocking peptide PEP-1275.
AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adapter-related protein complex 3 sigma-1 subunit; adapter-related protein complex 3 subunit sigma-1; adaptor related protein complex 3, sigma 1 subunit; Adaptor-related protein complex 3 subunit sigma-1; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; CLAPS3, Sigma3A; clathrin adaptor complex AP3, sigma-3A subunit; clathrin-associated/assembly/adapter protein, small 3; Clathrin-associated/assembly/adaptor protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD); Sigma-3A-adaptin; Sigma-adaptin 3a; Sigma3A-adaptin
AP3S1; CLAPS3; Sigma3A