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Product Details
PA5-120560
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human AP3S2 (NP_005820.1).
Conjugate
Form
Liquid
Concentration
2.21 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914132
Product Specific Information
Positive test controls include: HT-29, Mouse brain, Rat brain.
Immunogen sequence: MIQAILVFNN HGKPRLVRFY QRFPEEIQQQ IVRETFHLVL KRDDNICNFL EGGSLIGGSD YKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDKC FENVCELDLI FHMDKVHYIL QEVVMGGMVL ETNMNEIVAQ IEAQNRLEKS EGGLSAAPAR AVSAVKNINL PEIPRNINIG DLNIKVPNLS QFV
Target Information
AP3S2 (Adaptor Related Protein Complex 3 Subunit Sigma 2) is a Protein Coding gene. Among its related pathways are Lysosome. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is AP3S1. Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adapter-related protein complex 3 sigma-2 subunit; adapter-related protein complex 3 subunit sigma-2; adaptor complex sigma3B; adaptor related protein complex 3, sigma 2 subunit; Adaptor-related protein complex 3 subunit sigma-2; adaptor-related protein complex 3, sigma 2 subunit; adaptor-related protein complex AP-3, sigma 2 subunit; AP-3 complex sigma-3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; FLJ35955; sigma 3B; Sigma-3B-adaptin; Sigma-adaptin 3b; Sigma3B-adaptin
Gene Aliases: [s]3B; AP3S2; AP3S3; sigma3b
UniProt ID: (Human) P59780, (Mouse) Q8BSZ2
Entrez Gene ID: (Human) 10239, (Rat) 683402, (Mouse) 11778
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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