Immunofluorescent analysis of APBB2 showing staining in the cytoplasm and nucleus of H1299 cells. H1299 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using an APBB2 polyclonal antibody (Product # PA5-29111) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10µm.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 125 and 370 of Human APBB2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29111 targets APBB2 in WB applications and shows reactivity with Human samples.
The PA5-29111 immunogen is recombinant protein fragment corresponding to a region within amino acids 125 and 370 of Human APBB2.
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.
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