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Alomone Labs, LTD
KCNH5 (EAG-2) Polyclonal Antibody
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Product Details
APC-053-50UL
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EDPKGSDSENSVTKNPLRK,corresponding to amino acid residues 842-860 of rat KCNH5, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA, 5% sucrose
Contains
0.025% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ether a-go-go K+ channel 2; ether-a-go-go 2; Ether-a-go-go potassium channel 2; ether-a-go-go-related potassium channel 2; hEAG2; potassium channel, voltage gated eag related subfamily H, member 5; Potassium voltage-gated channel subfamily H member 5; potassium voltage-gated channel, subfamily H (eag-related), member 5; rEAG2; unnamed protein product; Voltage-gated delayed rectifier potassium channel KCNH5; Voltage-gated potassium channel subunit Kv10.2; voltage-gated; family H
Gene Aliases: DEE112; EAG2; H-EAG2; hEAG2; KCNH5; Kv10.2
UniProt ID: (Human) Q8NCM2, (Rat) Q9EPI9
Entrez Gene ID: (Human) 27133, (Rat) 171146
ion transport
potassium ion transport
regulation of G2/M transition of mitotic cell cycle
ion transmembrane transport
regulation of membrane potential
transmembrane transport
potassium ion transmembrane transport
phosphorelay signal transduction system
signal transduction by protein phosphorylation
regulation of ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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