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CD68 Monoclonal Antibody (Y1/82A), APC
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FIGURE: 1 / 1
CD68 Antibody (APC-65187100TST) in Flow
1X10^6 human peripheral blood monocytes were intracellularly stained with 10 µL/test APC Anti-Human CD68 (Product # APC-65187100TST), Clone:Y1/82A) (red) or isotype control antibody (blue). Cells were fixed with 4% PFA and permeabilized with 0.1% Triton X-100.
Product Details
APC-65187100TST
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
Y1/82A
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
10 µL/Test
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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