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          • Primary Antibodies ›
          • APC15 Antibodies

          Invitrogen

          APC15 Polyclonal Antibody

          View all (2) APC15 antibodies

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          Cite APC15 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          APC15 Antibody in Immunocytochemistry (ICC/IF)
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          APC15 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          APC15 Antibody (PA5-57736) in ICC/IF

          Immunofluorecent analysis of APC15 in human cell line U-2 OS using APC15 Polyclonal Antibody (Product # PA5-57736). Staining shows localization to nucleoplasm and vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          APC15 Antibody in Immunocytochemistry (ICC/IF)
          APC15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          APC15 Antibody in Western Blot (WB)
          APC15 Polyclonal Antibody

          Product Details

          PA5-57736

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human APC15. Recombinant protein control fragment (Product #RP-97313).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2638066

          Product Specific Information

          Immunogen sequence: PSLFPRVTET LWFNLDRPCV EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEED

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          Target Information

          ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Anaphase-promoting complex subunit 15; APC15

          View more View less

          Gene Aliases: ANAPC15; APC15; C11orf51; HSPC020

          View more View less

          UniProt ID: (Human) P60006

          View more View less

          Entrez Gene ID: (Human) 25906

          View more View less

          Function(s)
          protein binding
          Process(es)
          regulation of mitotic cell cycle anaphase-promoting complex-dependent catabolic process cell division regulation of meiotic cell cycle protein K48-linked ubiquitination protein K11-linked ubiquitination regulation of mitotic cell cycle spindle assembly checkpoint protein branched polyubiquitination
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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