|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal residues of human APG10 protein.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18292 detects APG10 from human samples.
PA1-18292 has been successfully used in immunohistochemistry and immunofluorescence procedures.
The PA1-18292 immunogen is a synthetic peptide corresponding to the C-terminal residues of human APG10 protein.
Reconstitute with 100 ul of distilled water.
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 .-ATG5 . conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.