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Rockland
APG7 Polyclonal Antibody
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Product Details
600-401-487
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 550-575 of Human Apg7 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Reactivity occurs against human Apg7 protein. However, BLAST analysis indicates 100% homology (12/12) for this protein from human, chimpanzee, mouse, rat, dog, and chicken sources. The core amino acids of the immunogen, G-D-S-T-R-D-R-T are 100% identical (8/8) in D. melanogaster. Reactivity with Apg7 proteins from other sources is not known.
Target Information
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APG7; APG7 autophagy 7-like; APG7-like; AT5G45900; ATAPG7; ATATG7; ATG12-activating enzyme E1 ATG7; AUTOPHAGY 7; AUTOPHAGY-RELATED 7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; K15I22.10; K15I22_10; PEROXISOME UNUSUAL POSITIONING 4; PEUP4; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7; unnamed protein product
Gene Aliases: APG7-LIKE; APG7L; ATG7; GSA7; SCAR31
UniProt ID: (Human) O95352
Entrez Gene ID: (Human) 10533
autophagosome assembly
mitophagy
protein lipidation
autophagy
cellular response to nitrogen starvation
cellular response to starvation
positive regulation of catabolic process
protein transport
macroautophagy
positive regulation of protein modification process
response to nutrient levels
protein modification by small protein conjugation
cellular response to stress
piecemeal microautophagy of nucleus
regulation of circadian rhythm
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of protein catabolic process
rhythmic process
defense response to virus
regulation of macromolecule metabolic process
cellular response to hyperoxia
regulation of primary metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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