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Invitrogen
APITD1 Polyclonal Antibody
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FIGURE: 1 / 5
APITD1 Antibody (PA5-24846) in IHC (P)
Immunohistochemistry analysis of APITD1 in formalin fixed and paraffin embedded brain tissue. Samples were incubated with APITD1 polyclonal antibody (Product # PA5-24846) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24846
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 48-74 amino acids from the central region of human APITD1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Apoptosis-inducing TAF9-like domain-containing protein 1; Apoptosis-inducing TAF9-like domain-containing protein 1 homolog; CENP-S; Centromere protein S; FANCM-associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa; ortholog of human apoptosis-inducing, TAF9-like domain 1 APITD1
Gene Aliases: 2610040C18Rik; 2810407L01Rik; APITD1; CENP-S; CENPS; FAAP16; MHF1
UniProt ID: (Human) Q8N2Z9, (Mouse) Q9D084
Entrez Gene ID: (Human) 378708, (Mouse) 69928
resolution of meiotic recombination intermediates
DNA repair
mitotic recombination
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic nuclear division
replication fork processing
positive regulation of protein ubiquitination
CENP-A containing nucleosome assembly
interstrand cross-link repair
cell division
kinetochore assembly
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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