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APLP1 Antibody (PA5-48028) in WB
Western blot analysis of APLP1 in 0.2 mg/mL human brain (hippocampus) and mouse brain (hippocampus). Samples were incubated in APLP1 polyclonal antibody (Product # PA5-48028 using a dilution of 25 µg/mL. A specific band was detected for APLP-1 at approximately 119 kDa (as indicated). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
Product Details
PA5-48028
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human APLP-1 Gln34-Glu580
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2608602
Product Specific Information
In Western blots, approximately 15% cross-reactivity with recombinant mouse APLP-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amyloid beta (A4) precursor-like protein 1; Amyloid beta precursor like protein 1; amyloid precursor-like protein 1; Amyloid-like protein 1; APLP; APLP 1; APLPAPLP-1; C30
Gene Aliases: APLP; APLP1
UniProt ID: (Human) P51693
Entrez Gene ID: (Human) 333
Molecular Function:
protease inhibitor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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