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APOBEC3A/APOBEC3B Antibody (PA5-104035) in IHC (P)
Immunohistochemistry analysis of APOBEC3A/APOBEC3B in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APOBEC3A/APOBEC3B polyclonal antibody (Product # PA5-104035) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104035
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human APOBEC3A(Accession P31941), corresponding to amino acid residues I26-L76.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853365
Product Specific Information
Antibody detects endogenous levels of total APOBEC3A/B.
Target Information
PHO3 is a member of the cytidine deaminase gene family. The PHO3 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A3A; A3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3A; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; bK150C 2.2; cytidine deaminase; DNA dC->dU-editing enzyme APOBEC-3A; DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 1; phorbolin 2; phorbolin 3; Phorbolin-1; Phorbolin-1-related protein; Phorbolin-2/3; probable DNA dC->dU-editing enzyme APOBEC-3A; probable DNA dC->dU-editing enzyme APOBEC-3B
Gene Aliases: A3A; A3B; APOBEC1L; APOBEC3A; APOBEC3B; ARCD3; ARP3; ARP4; bK150C2.1; bK150C2.2; DJ742C19.2; PHRBN; PHRBNL
UniProt ID: (Human) P31941, (Human) Q9UH17
Entrez Gene ID: (Human) 200315, (Human) 9582
cytidine deamination
negative regulation of transposition
clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine
negative regulation of viral genome replication
innate immune response
defense response to virus
DNA cytosine deamination
cellular response to xenobiotic stimulus
DNA demethylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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