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Invitrogen
APOBEC3B Polyclonal Antibody
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Product Details
PA5-11430
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 299-330 amino acids from the C-terminal region of human APOBEC3B (PHO3)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A3B; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; Apolipoprotein B mRNA-editing complex 3; Arp3; bK150C 2.2; bK150C2.2; CEM-15; CEM15; cytidine deaminase; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 2; phorbolin 3; Phorbolin-1-related protein; Phorbolin-2/3; probable DNA dC->dU-editing enzyme APOBEC-3B; recovery from Friend virus 3
Gene Aliases: A3B; APOBEC1L; Apobec3; APOBEC3B; ARCD3; Arp3; ARP4; BC003314; bK150C2.2; Cem15; DJ742C19.2; PHRBNL; Rfv3
UniProt ID: (Human) Q9UH17, (Mouse) Q99J72
Entrez Gene ID: (Human) 9582, (Mouse) 80287
RNA binding
catalytic activity
cytidine deaminase activity
protein binding
zinc ion binding
hydrolase activity
metal ion binding
GTP cyclohydrolase activity
tRNA-specific adenosine deaminase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
poly(A) RNA binding
deoxycytidine deaminase activity
tRNA-specific adenosine-34 deaminase activity
RNA processing factor
immune system process
negative regulation of transposition, RNA-mediated
negative regulation of macromolecule biosynthetic process
cytidine to uridine editing
clearance of foreign intracellular DNA
innate immune response
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
defense response to virus
DNA cytosine deamination
hematopoietic progenitor cell differentiation
metabolic process
negative regulation of transposition
negative regulation of viral genome replication
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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