Sequence homology: Human: 100%; Pig: 79%
This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
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Protein Aliases: A3F; apolipoprotein B editing enzyme catalytic polypeptide-like 3F; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3F; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation
Gene Aliases: A3F; APOBEC3F; ARP8; BK150C2.4.MRNA; KA6
UniProt ID: (Human) Q8IUX4
Entrez Gene ID: (Human) 200316