Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:20,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:1,000 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
- | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
1:100-1:1,000 | View 2 publications 2 publications |
ELISA (ELISA) |
1:1,000-1:10,000 | - |
Immunoprecipitation (IP) |
1:100-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to a region within amino acids 255 and 317 of Human Apo E |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.66 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.025% Proclin 300 |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2544564 |
Recommended positive controls: HepG2, Conditional medium from differentiated human primary preadipocyte, human plasma.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Apo E (Apolipoprotein E) plays an important role in the metabolism of lipids in the plasma, and is also is a constituent of various plasma lipoprotein-lipid particles. The protein is synthesized in liver, brain, spleen, and the kidney, and concentrations are high in interstitial fluids, where it plays a role in distributing cholesterol from cells where cholesterol is in excess to cells which require cholesterol. Apo E also plays an important role in the formation of very low density lipoprotein and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13. 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apo-E; ApoE4; Apolipoprotein; Apolipoprotein E; apolipoprotein E3; apolipoprotein E4; Apoprotein; B2G1; BG; MGC1571
Gene Aliases: AD2; APO-E; APOE; LDLCQ5; LPG
UniProt ID: (Human) P02649
Entrez Gene ID: (Human) 348
Molecular Function:
apolipoprotein
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