Product References
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.
Viruses
Wang H,Peng W,Wang J,Zhang C,Zhao W,Ran Y,Yang X,Chen J,Li H
Thu Apr 20 00:00:00 UTC 2023
Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice.
Molecular therapy : the journal of the American Society of Gene Therapy
Yang YW,Poudel B,Frederick J,Dhillon P,Shrestha R,Ma Z,Wu J,Okamoto K,Kopp JB,Booten SL,Gattis D,Watt AT,Palmer M,Aghajan M,Susztak K
Wed Jul 06 00:00:00 UTC 2022
Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid.
Neurobiology of disease
Hok-A-Hin YS,Dijkstra AA,Rábano A,Hoozemans JJ,Castillo L,Seelaar H,van Swieten JC,Pijnenburg YAL,Teunissen CE,Del Campo M
Sat Oct 01 00:00:00 UTC 2022
Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid.
Neurobiology of disease
Hok-A-Hin YS,Dijkstra AA,Rábano A,Hoozemans JJ,Castillo L,Seelaar H,van Swieten JC,Pijnenburg YAL,Teunissen CE,Del Campo M
Sat Oct 01 00:00:00 UTC 2022
The key role of NLRP3 and STING in APOL1-associated podocytopathy.
The Journal of clinical investigation
Wu J,Raman A,Coffey NJ,Sheng X,Wahba J,Seasock MJ,Ma Z,Beckerman P,Laczkó D,Palmer MB,Kopp JB,Kuo JJ,Pullen SS,Boustany-Kari CM,Linkermann A,Susztak K
Fri Oct 15 00:00:00 UTC 2021
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Immunity
Wu J,Ma Z,Raman A,Beckerman P,Dhillon P,Mukhi D,Palmer M,Chen HC,Cohen CR,Dunn T,Reilly J,Meyer N,Shashaty M,Arany Z,Haskó G,Laudanski K,Hung A,Susztak K
Tue Nov 09 00:00:00 UTC 2021
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Immunity
Wu J,Ma Z,Raman A,Beckerman P,Dhillon P,Mukhi D,Palmer M,Chen HC,Cohen CR,Dunn T,Reilly J,Meyer N,Shashaty M,Arany Z,Haskó G,Laudanski K,Hung A,Susztak K
Tue Nov 09 00:00:00 UTC 2021
Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease.
Disease models & mechanisms
McCarthy GM,Blasio A,Donovan OG,Schaller LB,Bock-Hughes A,Magraner JM,Suh JH,Tattersfield CF,Stillman IE,Shah SS,Zsengeller ZK,Subramanian B,Friedman DJ,Pollak MR
Sun Aug 01 00:00:00 UTC 2021
Alterations in plasma membrane ion channel structures stimulate NLRP3 inflammasome activation in APOL1 risk milieu.
The FEBS journal
Jha A,Kumar V,Haque S,Ayasolla K,Saha S,Lan X,Malhotra A,Saleem MA,Skorecki K,Singhal PC
Fri May 01 00:00:00 UTC 2020
Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function.
Journal of the American Society of Nephrology : JASN
Datta S,Kataria R,Zhang JY,Moore S,Petitpas K,Mohamed A,Zahler N,Pollak MR,Olabisi OA
Tue Sep 01 00:00:00 UTC 2020
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.
eLife
Giovinazzo JA,Thomson RP,Khalizova N,Zager PJ,Malani N,Rodriguez-Boulan E,Raper J,Schreiner R
Tue May 19 00:00:00 UTC 2020
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.
eLife
Giovinazzo JA,Thomson RP,Khalizova N,Zager PJ,Malani N,Rodriguez-Boulan E,Raper J,Schreiner R
Tue May 19 00:00:00 UTC 2020
Disrupted apolipoprotein L1-miR193a axis dedifferentiates podocytes through autophagy blockade in an APOL1 risk milieu.
American journal of physiology. Cell physiology
Kumar V,Ayasolla K,Jha A,Mishra A,Vashistha H,Lan X,Qayyum M,Chinnapaka S,Purohit R,Mikulak J,Saleem MA,Malhotra A,Skorecki K,Singhal PC
Thu Aug 01 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.
Scientific reports
Kumar V,Paliwal N,Ayasolla K,Vashistha H,Jha A,Chandel N,Chowdhary S,Saleem MA,Malhotra A,Chander PN,Skorecki K,Singhal PC
Tue Mar 05 00:00:00 UTC 2019
Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.
The American journal of pathology
Kumar V,Vashistha H,Lan X,Chandel N,Ayasolla K,Shoshtari SSM,Aslam R,Paliwal N,Abbruscato F,Mikulak J,Popik W,Atta MG,Chander PN,Malhotra A,Meyer-Schwesinger C,Skorecki K,Singhal PC
Thu Nov 01 00:00:00 UTC 2018
Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.
The American journal of pathology
Kumar V,Vashistha H,Lan X,Chandel N,Ayasolla K,Shoshtari SSM,Aslam R,Paliwal N,Abbruscato F,Mikulak J,Popik W,Atta MG,Chander PN,Malhotra A,Meyer-Schwesinger C,Skorecki K,Singhal PC
Thu Nov 01 00:00:00 UTC 2018
Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.
The American journal of pathology
Kumar V,Vashistha H,Lan X,Chandel N,Ayasolla K,Shoshtari SSM,Aslam R,Paliwal N,Abbruscato F,Mikulak J,Popik W,Atta MG,Chander PN,Malhotra A,Meyer-Schwesinger C,Skorecki K,Singhal PC
Thu Nov 01 00:00:00 UTC 2018
Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.
The American journal of pathology
Kumar V,Vashistha H,Lan X,Chandel N,Ayasolla K,Shoshtari SSM,Aslam R,Paliwal N,Abbruscato F,Mikulak J,Popik W,Atta MG,Chander PN,Malhotra A,Meyer-Schwesinger C,Skorecki K,Singhal PC
Thu Nov 01 00:00:00 UTC 2018
APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress.
Bioscience reports
Wen H,Kumar V,Lan X,Shoshtari SSM,Eng JM,Zhou X,Wang F,Wang H,Skorecki K,Xing G,Wu G,Luo H,Malhotra A,Singhal PC
Fri Aug 31 00:00:00 UTC 2018
APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress.
Bioscience reports
Wen H,Kumar V,Lan X,Shoshtari SSM,Eng JM,Zhou X,Wang F,Wang H,Skorecki K,Xing G,Wu G,Luo H,Malhotra A,Singhal PC
Fri Aug 31 00:00:00 UTC 2018
APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress.
Bioscience reports
Wen H,Kumar V,Lan X,Shoshtari SSM,Eng JM,Zhou X,Wang F,Wang H,Skorecki K,Xing G,Wu G,Luo H,Malhotra A,Singhal PC
Fri Aug 31 00:00:00 UTC 2018
APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress.
Bioscience reports
Wen H,Kumar V,Lan X,Shoshtari SSM,Eng JM,Zhou X,Wang F,Wang H,Skorecki K,Xing G,Wu G,Luo H,Malhotra A,Singhal PC
Fri Aug 31 00:00:00 UTC 2018
Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu.
American journal of physiology. Renal physiology
Mishra A,Ayasolla K,Kumar V,Lan X,Vashistha H,Aslam R,Hussain A,Chowdhary S,Marashi Shoshtari S,Paliwal N,Popik W,Saleem MA,Malhotra A,Meggs LG,Skorecki K,Singhal PC
Tue May 01 00:00:00 UTC 2018
Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu.
American journal of physiology. Renal physiology
Mishra A,Ayasolla K,Kumar V,Lan X,Vashistha H,Aslam R,Hussain A,Chowdhary S,Marashi Shoshtari S,Paliwal N,Popik W,Saleem MA,Malhotra A,Meggs LG,Skorecki K,Singhal PC
Tue May 01 00:00:00 UTC 2018
