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          • Primary Antibodies ›
          • DIP13B Antibodies

          Abnova

          APPL2 Polyclonal Antibody, MaxPab™

          View all (15) DIP13B antibodies

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          Cite APPL2 Polyclonal Antibody, MaxPab™

          Additional Information:
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          • Antibody Testing Data (1)
          APPL2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          APPL2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          APPL2 Antibody (H00055198-B01P) in WB

          Western Blot analysis of APPL2 expression in transfected 293T cell line by APPL2 MaxPab polyclonal antibody. Lane 1: APPL2 transfected lysate(73.04 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          APPL2 Antibody in Western Blot (WB)

          Product Details

          H00055198-B01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          10-100 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          APPL2 (AAH33731.1, 1 a.a. approximately 664 a.a) full-length human protein.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Product may be used with Western Blot (Transfected lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: MPAVDKLLLE EALQDSPQTR SLLSVFEEDA GTLTDYTNQL LQAMQRVYGA QNEMCLATQQ LSKQLLAYEK QNFALGKGDE EVISTLHYFS KVVDELNLLH TELAKQLADT MVLPIIQFRE KDLTEVSTLK DLFGLASNEH DLSMAKYSRL PKKKENEKVK TEVGKEVAAA RRKQHLSSLQ YYCALNALQY RKQMAMMEPM IGFAHGQINF FKKGAEMFSK RMDSFLSSVA DMVQSIQVEL EAEAEKMRVS QQELLSVDES VYTPDSDVAA PQINRNLIQK AGYLNLRNKT GLVTTTWERL YFFTQGGNLM CQPRGAVAGG LIQDLDNCSV MAVDCEDRRY CFQITTPNGK SGIILQAESR KENEEWICAI NNISRQIYLT DNPEAVAIKL NQTALQAVTP ITSFGKKQES SCPSQNLKNS EMENENDKIV PKVTASLPEA EELIAPGTPI QFDIVLPATE FLDQNRGSRR TNPFGETEDE SFPEAEDSLL QQMFIVRFLG SMAVKTDSTT EVIYEAMRQV LAARAIHNIF RMTESHLMVT SQSLRLIDPQ TQVSRANFEL TSVTQFAAHQ ENKRLVGFVI RVPESTGEES LSTYIFESNS EGEKICYAIN LGKEIIEVQK DPEALAQLML SIPLTNDGKY VLLNDQPDDD DGNPNEHRGA ESEA

          Target Information

          Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Adapter protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DCC-interacting protein 13-beta; DIP13 beta; Dip13-beta; unnamed protein product

          View more View less

          Gene Aliases: APPL2; DIP13B; RGD1563028

          View more View less

          UniProt ID: (Human) Q8NEU8, (Rat) B4F779

          View more View less

          Entrez Gene ID: (Human) 55198, (Rat) 362860

          View more View less

          Function(s)
          phosphatidylserine binding protein binding phosphatidylinositol binding identical protein binding protein homodimerization activity macromolecular complex binding scaffold/adaptor protein
          Process(es)
          diet induced thermogenesis protein import into nucleus signal transduction transforming growth factor beta receptor signaling pathway cold acclimation regulation of fibroblast migration signaling adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway cellular response to hepatocyte growth factor stimulus homeostatic process glucose homeostasis regulation of innate immune response negative regulation of fatty acid oxidation negative regulation of glucose import negative regulation of neurogenesis protein homotetramerization positive regulation of phagocytosis, engulfment positive regulation of cold-induced thermogenesis negative regulation of cytokine production involved in inflammatory response negative regulation of cellular response to insulin stimulus positive regulation of macropinocytosis positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis regulation of G1/S transition of mitotic cell cycle negative regulation of neural precursor cell proliferation cell proliferation
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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