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Alomone Labs, LTD
Platelet-activating factor receptor (extracellular) Polyclonal Antibody, FITC
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FIGURE: 1 / 4
Platelet-activating factor receptor (extracellular) Antibody (APR-055-F-50UL) in Flow
Cell surface detection of PAFR by direct flow cytometry in live intact human MEG-01 megakaryoblastic leukemia cells: - (black line) cells. (red) Cells + Rabbit IgG Isotype Control-FITC. (green) Cells + Anti-Platelet-activating factor receptor (extracellular)-FITC Antibody (#APR-055-F), (2.5 µg).
Product Details
APR-055-F-50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)ELGYQTNFHQAINDAH, corresponding to amino acid residues 259-274 of mouse PTAFR, Extracellular, 3rd loop
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 15 µL or 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; PAF receptor; PAF-R; PAFr; Platelet-activating factor receptor; unnamed protein product
Gene Aliases: PAFR; PTAFR
UniProt ID: (Human) P25105, (Mouse) Q62035, (Rat) P46002
Entrez Gene ID: (Human) 5724, (Mouse) 19204, (Rat) 58949
lipopolysaccharide binding
lipopolysaccharide receptor activity
G-protein coupled receptor activity
platelet activating factor receptor activity
protein binding
phospholipid binding
G-protein coupled purinergic nucleotide receptor activity
signal transducer activity
mitogen-activated protein kinase binding
G-protein coupled receptor
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
cytokine production
pattern recognition receptor signaling pathway
positive regulation of phospholipase C activity
phosphatidylinositol-mediated signaling
positive regulation of inositol phosphate biosynthetic process
positive regulation of voltage-gated chloride channel activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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