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Abnova
APTX Polyclonal Antibody, MaxPab™
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Product Details
H00054840-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
APTX (NP_778242.1, 1 a.a. approximately 254 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVNELYPYIV EFEEEAKNPG LETHRKRKRS GNSDSIERDA AQEAEAGTGL EPGSNSGQCS VPLKKGKDAP IKKESLGHWS QGLKISMQDP KMQVYKDEQV VVIKDKYPKA RYHWLVLPWT SISSLKAVAR EHLELLKHMH TVGEKVIVDF AGSSKLRFRL GYHAIPSMSH VHLHVISQDF DSPCLKNKKH WNSFNTEYFL ESQAVIEMVQ EAGRVTVRDG MPELLKLPLR CHECQQLLPS IPQLKEHLRK HWTQ
Target Information
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aprataxin; FHA-HIT; Forkhead-associated domain histidine triad-like protein; major isoform; minor isoform; unnamed protein product
Gene Aliases: AOA; AOA1; APTX; AXA1; EAOH; EOAHA; FHA-HIT
UniProt ID: (Human) Q7Z2E3
Entrez Gene ID: (Human) 54840
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
double-stranded RNA binding
catalytic activity
protein binding
zinc ion binding
phosphoglycolate phosphatase activity
hydrolase activity
mismatched DNA binding
DNA 5'-adenosine monophosphate hydrolase activity
polynucleotide 3'-phosphatase activity
metal ion binding
phosphoprotein binding
DNA-3'-diphospho-5'-guanosine diphosphatase
single-strand break-containing DNA binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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