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AQP1 Polyclonal Antibody

View all (32) Aquaporin 1 antibodies

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AQP1 Polyclonal Antibody

Product Details

BS-1506R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:500
-

Flow Cytometry (Flow)

1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human AQP1, amino acids 181-269.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 28 kda erythrocyte integral membrane protein homolog; AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; bloodgroup CO protein; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Colton blood group antigen; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; unnamed protein product; Urine water channel; water channel protein for red blood cells and kidney proximal tubule

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Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO

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UniProt ID: (Human) P29972, (Mouse) Q02013, (Rat) P29975

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Entrez Gene ID: (Human) 358, (Mouse) 11826, (Rat) 25240

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Function(s)
intracellular cGMP activated cation channel activity potassium channel activity water transmembrane transporter activity protein binding ammonium transmembrane transporter activity potassium ion transmembrane transporter activity glycerol transmembrane transporter activity water channel activity channel activity transmembrane transporter activity nitric oxide transmembrane transporter activity carbon dioxide transmembrane transporter activity identical protein binding ephrin receptor binding hydrogen peroxide channel activity transporter activity glycerol channel activity transporter
Process(es)
renal water homeostasis glomerular filtration renal water transport potassium ion transport water transport cell volume homeostasis hyperosmotic response cellular water homeostasis fibroblast migration positive regulation of fibroblast migration carbon dioxide transport glycerol transport cell migration sensory perception of pain cellular homeostasis cGMP-mediated signaling lateral ventricle development pancreatic juice secretion nitric oxide transport establishment or maintenance of actin cytoskeleton polarity secretion by cell cerebrospinal fluid secretion secretory granule organization cellular response to UV transepithelial water transport carbon dioxide transmembrane transport wound healing odontogenesis negative regulation of apoptotic process lipid digestion positive regulation of angiogenesis positive regulation of saliva secretion positive regulation of fibroblast proliferation camera-type eye morphogenesis defense response to Gram-negative bacterium multicellular organismal water homeostasis corticotropin secretion establishment of localization in cell transmembrane transport renal water absorption cellular response to hydrogen peroxide cellular response to mechanical stimulus cellular response to copper ion cellular response to mercury ion cellular response to retinoic acid cellular response to cAMP cellular response to hypoxia cellular response to salt stress cellular hyperosmotic response cellular response to dexamethasone stimulus cellular response to nitric oxide potassium ion transmembrane transport metanephric descending thin limb development metanephric proximal straight tubule development metanephric proximal convoluted tubule segment 2 development metanephric glomerulus vasculature development ammonium transmembrane transport hydrogen peroxide transmembrane transport cation transmembrane transport cGMP biosynthetic process transport positive regulation of lamellipodium assembly positive regulation of epithelial cell migration organic cation transport ammonium transport water homeostasis positive regulation of cell migration cellular response to stress carbohydrate transmembrane transport response to drug negative regulation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to inorganic substance maintenance of symbiont-containing vacuole by host response to hormone hyperosmotic salinity response response to estrogen
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