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Proteintech
ARF1 Polyclonal Antibody
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Product Details
10790-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARF1 Fusion Protein Ag1244 (1-181 aa encoded by BC009247)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can bind ARFs for the close sequences.
Immunogen sequence: MGNIFANLF KGLFGKKEMR ILMVGLDAAG KTTILYKLKL GEIVTTIPTI GFNVETVEYK NISFTVWDVG GQDKIRPLWR HYFQNTQGLI FVVDSNDRER VNEAREELMR MLAEDELRDA VLLVFANKQD LPNAMNAAEI TDKLGLHSLR HRNWYIQATC ATSGDGLYEG LDWLSNQLRN QK (1-181 aa encoded by BC009247)
Target Information
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP ribosylation factor 1; ADP-ribosylation factor (ARF1); ADP-ribosylation factor 1; small GTP binding protein; unnamed protein product
Gene Aliases: ARF1; PVNH8
UniProt ID: (Human) P84077, (Mouse) P84078, (Rat) P84079
Entrez Gene ID: (Human) 375, (Mouse) 11840, (Rat) 64310
regulation of receptor internalization
cellular copper ion homeostasis
intracellular protein transport
protein transport
vesicle-mediated transport
regulation of Arp2/3 complex-mediated actin nucleation
long term synaptic depression
dendritic spine organization
cellular response to virus
mitotic cleavage furrow ingression
transport
actin filament organization
small GTPase mediated signal transduction
very-low-density lipoprotein particle assembly
positive regulation of catalytic activity
positive regulation of endocytosis
positive regulation of calcium ion-dependent exocytosis
positive regulation of protein secretion
Golgi to transport vesicle transport
positive regulation of dendritic spine development
synaptic vesicle budding
lysosomal membrane organization
positive regulation of sodium ion transmembrane transport
positive regulation of late endosome to lysosome transport
positive regulation of ER to Golgi vesicle-mediated transport
regulation of phospholipid metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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