The antibody is specific to ARF3. It has no cross reaction to other ARF members.
ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
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Protein Aliases: ADP-ribosylation factor 3; ANX4; ANXA4; Liver regeneration-related protein LRRG202; small GTP binding protein
Gene Aliases: 5430400P17Rik; Ac1-253; AI854770; ARF3
Molecular Function: G-protein