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Proteintech
ARFGEF2 Polyclonal Antibody
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Product Details
31277-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARFGEF2 fusion protein Ag35396
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PIQSKPQSPV IQAAAVSPKF VRLKHSQAQS KPTTPEKTDL TNGEHARSDS GKVSTENGDA PRERGSSLSG TDDGAQEVVK DILEDVVTSA IKEAAEKHGL TEPERVLGEL ECQECAIPPG VDENSQTNGI ADDRQSLSSA DNLESDAQGH QVAARFSHVL
Target Information
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP ribosylation factor guanine nucleotide exchange factor 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange protein 2; unnamed protein product
Gene Aliases: AI463430; ARFGEF2; ARFGEP2; AW493672; BIG2; dJ1164I10.1; E230011G24Rik; PVNH2
UniProt ID: (Human) Q9Y6D5, (Mouse) A2A5R2
Entrez Gene ID: (Human) 10564, (Mouse) 99371
receptor recycling
exocytosis
Golgi to plasma membrane transport
endosome organization
endomembrane system organization
protein transport
vesicle-mediated transport
regulation of ARF protein signal transduction
positive regulation of tumor necrosis factor production
intracellular signal transduction
transport
positive regulation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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