Proteintech

ARG1 Polyclonal Antibody

ARG1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 27

ARG1 Antibody (16001-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells using 16001-1-AP (ARG1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ARG1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ARG1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16001-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 152 publications 152 publications

Immunohistochemistry (IHC)

View 34 publications 34 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

Immunocytochemistry (ICC/IF)

1:20-1:200

View 91 publications 91 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ARG1 Fusion Protein Ag8595 (1-236 aa encoded by BC005321)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSAKSRTIG IIGAPFSKGQ PRGGVEEGPT VLRKAGLLEK LKEQECDVKD YGDLPFADIP NDSPFQIVKN PRSVGKASEQ LAGKVAEVKK NGRISLVLGG DHSLAIGSIS GHARVHPDLG VIWVDAHTDI NTPLTTTSGN LHGQPVSFLL KELKGKIPDV PGFSWVTPCI SAKDIVYIGL RDVDPGEHYI LKTLGIKYFS MTEVTRTVNT AVAITLACFG LAREGNHKPI DYLNPPK (1-236 aa encoded by BC005321)

Target Information

Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle. The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production. In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells. In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported. In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a). Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas. Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Myricetin improves pathological changes in 3×Tg-AD mice by regulating the mitochondria-NLRP3 inflammasome-microglia channel by targeting P38 MAPK signaling pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Liu P,Zhou Y,Shi J,Wang F,Yang X,Zheng X,Wang Y,He Y,Xie X,Pang X

Sat Jul 01 00:00:00 UTC 2023

miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Cao ZR,Zheng WX,Jiang YX,Chai H,Gong JH,Zhao MJ,Yan P,Liu YY,Liu XY,Huang ZT,Yang H,Peng DD,Zong KZ,Wu ZJ

Wed Mar 01 00:00:00 UTC 2023

Influence of the irradiated pulmonary microenvironment on macrophage and T cell dynamics.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Groves AM,Misra R,Clair G,Hernady E,Olson H,Orton D,Finkelstein J,Marples B,Johnston CJ

Thu Jun 01 00:00:00 UTC 2023

BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.

Neurochemical research

Wei X,Huang C,Chen K,Liu S,Wang M,Yang L,Wang Y

Fri Sep 01 00:00:00 UTC 2023

BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.

Neurochemical research

Wei X,Huang C,Chen K,Liu S,Wang M,Yang L,Wang Y

Fri Sep 01 00:00:00 UTC 2023

The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis.

International immunopharmacology

Hu WM,Liu SQ,Zhu KF,Li W,Yang ZJ,Yang Q,Zhu ZC,Chang J

Tue Aug 01 00:00:00 UTC 2023

Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis.

Advanced materials (Deerfield Beach, Fla.)

Zhang Y,Sheng R,Chen J,Wang H,Zhu Y,Cao Z,Zhao X,Wang Z,Liu C,Chen Z,Zhang P,Kuang B,Zheng H,Shen C,Yao Q,Zhang W

Mon May 01 00:00:00 UTC 2023

TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF-κB Signaling Pathway.

Neuroendocrinology

Liu Y,Yang H,Wu X,Kuang Y,Ban B,Liang Z,Li L,Huang Z,Lu D,Qin Y,Liang X,Luo Z

Fri Mar 24 00:00:00 UTC 2023

Hypoxic ASCs-derived Exosomes Attenuate Colitis by Regulating Macrophage Polarization via miR-216a-5p/HMGB1 Axis.

Inflammatory bowel diseases

Qian W,Huang L,Xu Y,Lu W,Wen W,Guo Z,Zhu W,Li Y

Mon Apr 03 00:00:00 UTC 2023

A novel transgenic mouse model expressing primate-specific nuclear choline acetyltransferase: insights into potential cholinergic vulnerability.

Scientific reports

AlQot HE,Rylett RJ

Tue Feb 21 00:00:00 UTC 2023

p53 inhibits the Urea cycle and represses polyamine biosynthesis in glioma cell lines.

Metabolic brain disease

Zhao Y,Chen Y,Wei L,Ran J,Wang K,Zhu S,Liu Q

Sat Apr 01 00:00:00 UTC 2023

Wutou decoction attenuates the synovial inflammation of collagen-induced arthritis rats via regulating macrophage M1/M2 type polarization.

Journal of ethnopharmacology

Lin W,Shen P,Huang Y,Han L,Ba X,Huang Y,Yan J,Li T,Xu L,Qin K,Chen Z,Tu S

Mon Jan 30 00:00:00 UTC 2023

Matrix metalloproteinase-21 promotes metastasis via increasing the recruitment and M2 polarization of macrophages in HCC.

Cancer science

Zhou J,Liu L,Hu X,Feng R,Zhao N,Zhang L,Hu W,Zhang J,Huang S,Liu L,Li W,Shan Y,Jin J

Wed Feb 01 00:00:00 UTC 2023

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.

Investigative ophthalmology & visual science

Shu N,Zhang Z,Wang X,Li R,Li W,Liu X,Zhang Q,Jiang Z,Tao L,Zhang L,Hou S

Mon May 01 00:00:00 UTC 2023

Hybrid Cell Membrane-Functionalized Matrixes for Modulating Inflammatory Microenvironment and Improving Bone Defect Repair.

Advanced healthcare materials

Qiao F,Lv Y

Sat Jul 01 00:00:00 UTC 2023

Spinal cannabinoid receptor 2 activation alleviates neuropathic pain by regulating microglia and suppressing P2X7 receptor.

Frontiers in molecular neuroscience

Zhou Y,Xu Y,Yang J,Yu Z,Wang W,Yuan M,Wang Y,Bai Q,Li Z

Tue Mar 28 00:00:00 UTC 2023

Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.

International journal of biological sciences

Wang S,Tian Z,Lu Y,Huang Z,Fan Y,Li B,Zheng H,Wu X,Wang M,Zhao J,Xie J

Mon Apr 17 00:00:00 UTC 2023

Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle.

eLife

Nasir NJM,Heemskerk H,Jenkins J,Hamadee NH,Bunte R,Tucker-Kellogg L

Fri Jun 02 00:00:00 UTC 2023

Danggui-Shaoyao-San Promotes Amyloid-β Clearance through Regulating Microglia Polarization via Trem2 in BV2 Cells.

Journal of integrative neuroscience

Chen G,Han M,Chen Y,Lei Y,Li M,Wang L,Wang C,Hu Y,Niu J,Yang C,Mo Y,Wang Q,Yang L,Chang X

Mon May 15 00:00:00 UTC 2023

Danggui-Shaoyao-San Promotes Amyloid-β Clearance through Regulating Microglia Polarization via Trem2 in BV2 Cells.

Journal of integrative neuroscience

Chen G,Han M,Chen Y,Lei Y,Li M,Wang L,Wang C,Hu Y,Niu J,Yang C,Mo Y,Wang Q,Yang L,Chang X

Mon May 15 00:00:00 UTC 2023

γ-Glutamylcysteine rescues mice from TNBS-driven inflammatory bowel disease through regulating macrophages polarization.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Zhou J,Yan X,Bi X,Lu S,Liu X,Yang C,Shi Y,Luo L,Yin Z

Wed Mar 01 00:00:00 UTC 2023

γ-Glutamylcysteine rescues mice from TNBS-driven inflammatory bowel disease through regulating macrophages polarization.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Zhou J,Yan X,Bi X,Lu S,Liu X,Yang C,Shi Y,Luo L,Yin Z

Wed Mar 01 00:00:00 UTC 2023

Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.

International immunopharmacology

Xie XM,Hao JJ,Shi JZ,Zhou YF,Liu PF,Wang F,Zheng XM,Yu XY,Wang CC,Yan Y,Du GH,Song JK,He YY,Pang XB

Mon May 01 00:00:00 UTC 2023

Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model.

International immunopharmacology

Xie XM,Hao JJ,Shi JZ,Zhou YF,Liu PF,Wang F,Zheng XM,Yu XY,Wang CC,Yan Y,Du GH,Song JK,He YY,Pang XB

Mon May 01 00:00:00 UTC 2023

α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously.

Drug design, development and therapy

Wu YJ,Zhang SS,Yin Q,Lei M,Wang QH,Chen WG,Luo TT,Zhou P,Ji CL

Fri Mar 03 00:00:00 UTC 2023

Modulation of gut microbiota alleviates cerebral ischemia/reperfusion injury in rats by inhibiting M1 polarization of microglia.

Frontiers in pharmacology

Li HJ,Li DQ,Zhang YL,Ding XF,Gao HT,Zhu Y,Liu J,Zhang LX,Chen J,Chen G,Yu Y

Sun May 28 00:00:00 UTC 2023

Human placental extract regulates polarization of macrophages via IRGM/NLRP3 in allergic rhinitis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Wo B,Du C,Yang Y,Qi H,Liang Z,He C,Yao F,Li X

Sat Apr 01 00:00:00 UTC 2023

Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.

Journal of ethnopharmacology

He P,Wang H,Cheng S,Hu F,Zhang L,Chen W,Xu Y,Zhang Y,Gu Y,Li Z,Jin Y,Liu X,Jia Y

Thu Oct 05 00:00:00 UTC 2023

Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.

Journal of ethnopharmacology

He P,Wang H,Cheng S,Hu F,Zhang L,Chen W,Xu Y,Zhang Y,Gu Y,Li Z,Jin Y,Liu X,Jia Y

Thu Oct 05 00:00:00 UTC 2023

Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.

Frontiers in bioengineering and biotechnology

Ge L,Wang K,Lin H,Tao E,Xia W,Wang F,Mao C,Feng Y

Tue Mar 21 00:00:00 UTC 2023

Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.

Metabolic brain disease

Hu H,Lu X,Huang L,He Y,Liu X,Wang Y,Duan C

Wed Feb 01 00:00:00 UTC 2023

Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.

Metabolic brain disease

Hu H,Lu X,Huang L,He Y,Liu X,Wang Y,Duan C

Wed Feb 01 00:00:00 UTC 2023

Fecal microbiota transplantation and short-chain fatty acids protected against cognitive dysfunction in a rat model of chronic cerebral hypoperfusion.

CNS neuroscience & therapeutics

Su SH,Chen M,Wu YF,Lin Q,Wang DP,Sun J,Hai J

Thu Jun 01 00:00:00 UTC 2023

Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.

PeerJ

Yi C,Wu S,Duan Q,Liu L,Li L,Luo Y,Wang A

Fri Mar 24 00:00:00 UTC 2023

Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.

PeerJ

Yi C,Wu S,Duan Q,Liu L,Li L,Luo Y,Wang A

Fri Mar 24 00:00:00 UTC 2023

Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.

PeerJ

Yi C,Wu S,Duan Q,Liu L,Li L,Luo Y,Wang A

Fri Mar 24 00:00:00 UTC 2023

Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.

PeerJ

Yi C,Wu S,Duan Q,Liu L,Li L,Luo Y,Wang A

Fri Mar 24 00:00:00 UTC 2023

Functional characterization of interleukin 4 and retinoic acid signaling crosstalk during alternative macrophage activation.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Pinos I,Yu J,Pilli N,Kane MA,Amengual J

Sat Apr 01 00:00:00 UTC 2023

Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.

Acta biomaterialia

Li Y,Zhang J,Wang C,Jiang Z,Lai K,Wang Y,Yang G

Wed Feb 01 00:00:00 UTC 2023

Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways.

Frontiers in pharmacology

Wang J,Gao H,Xie Y,Wang P,Li Y,Zhao J,Wang C,Ma X,Wang Y,Mao Q,Xia H

Tue Aug 08 00:00:00 UTC 2023

Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways.

Frontiers in pharmacology

Wang J,Gao H,Xie Y,Wang P,Li Y,Zhao J,Wang C,Ma X,Wang Y,Mao Q,Xia H

Tue Aug 08 00:00:00 UTC 2023

Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.

Journal of neuroinflammation

He D,Fu S,Ye B,Wang H,He Y,Li Z,Li J,Gao X,Liu D

Wed Mar 29 00:00:00 UTC 2023

Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.

CNS neuroscience & therapeutics

He JY,Li DD,Wen Q,Qin TY,Long H,Zhang SB,Zhang F

Tue Aug 01 00:00:00 UTC 2023

SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.

Journal of cardiovascular medicine (Hagerstown, Md.)

Li L,Hua C,Liu X,Wang Y,Zhao L,Zhang Y,Wang L,Su P,Yang MF,Xie B

Sat Apr 01 00:00:00 UTC 2023

SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.

Journal of cardiovascular medicine (Hagerstown, Md.)

Li L,Hua C,Liu X,Wang Y,Zhao L,Zhang Y,Wang L,Su P,Yang MF,Xie B

Sat Apr 01 00:00:00 UTC 2023

SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.

Journal of cardiovascular medicine (Hagerstown, Md.)

Li L,Hua C,Liu X,Wang Y,Zhao L,Zhang Y,Wang L,Su P,Yang MF,Xie B

Sat Apr 01 00:00:00 UTC 2023

SGLT2i alleviates epicardial adipose tissue inflammation by modulating ketone body-glyceraldehyde-3-phosphate dehydrogenase malonylation pathway.

Journal of cardiovascular medicine (Hagerstown, Md.)

Li L,Hua C,Liu X,Wang Y,Zhao L,Zhang Y,Wang L,Su P,Yang MF,Xie B

Sat Apr 01 00:00:00 UTC 2023

Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.

Immunology

Gou Y,Wang H,Wang T,Wang H,Wang B,Jiao N,Yu Y,Cao Y,Wang H,Zhang Z

Wed Mar 01 00:00:00 UTC 2023

Host genetic background regulates the capacity for anti-tumor antibody-dependent phagocytosis.

bioRxiv : the preprint server for biology

Glassbrook JE,Hackett JB,Muñiz MC,Bross M,Dyson G,Movahhedin N,Ullrich A,Gibson HM

Tue May 09 00:00:00 UTC 2023

Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury.

BMC genomics

Cao J,Pan C,Zhang J,Chen Q,Li T,He D,Cheng X

Wed Apr 05 00:00:00 UTC 2023

Regulatory Effects of Three-Dimensional Cultured Lipopolysaccharide-Pretreated Periodontal Ligament Stem Cell-Derived Secretome on Macrophages.

International journal of molecular sciences

Su Y,Ai S,Shen Y,Cheng W,Xu C,Sui L,Zhao Y

Mon Apr 10 00:00:00 UTC 2023

Celastrol-loaded biomimetic nanodrug ameliorates APAP-induced liver injury through modulating macrophage polarization.

Journal of molecular medicine (Berlin, Germany)

Zheng J,Yang N,Wan Y,Cheng W,Zhang G,Yu S,Yang B,Liu X,Chen X,Ding X,Wu L,Yu X

Thu Jun 01 00:00:00 UTC 2023

Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.

Molecular neurobiology

Xu Y,Zhu ZH,Xu X,Sun HT,Zheng HM,Zhang JL,Wang HH,Fang JW,Liu YZ,Huang LL,Song ZW,Liu JB

Tue Aug 01 00:00:00 UTC 2023

Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area.

Molecular neurobiology

Xu Y,Zhu ZH,Xu X,Sun HT,Zheng HM,Zhang JL,Wang HH,Fang JW,Liu YZ,Huang LL,Song ZW,Liu JB

Tue Aug 01 00:00:00 UTC 2023

Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.

Journal of neuroinflammation

Yuan F,Peng W,Yang Y,Xu J,Liu Y,Xie Y,Huang T,Shi C,Ding Y,Li C,Qin T,Xie S,Zhu F,Lu H,Huang J,Hu J

Fri Jun 30 00:00:00 UTC 2023

T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.

Journal for immunotherapy of cancer

Wang X,Zhang Q,Zhou J,Xiao Z,Liu J,Deng S,Hong X,Huang W,Cai M,Guo Y,Huang J,Wang Y,Lin L,Zhu K

Wed Feb 01 00:00:00 UTC 2023

T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.

Journal for immunotherapy of cancer

Wang X,Zhang Q,Zhou J,Xiao Z,Liu J,Deng S,Hong X,Huang W,Cai M,Guo Y,Huang J,Wang Y,Lin L,Zhu K

Wed Feb 01 00:00:00 UTC 2023

Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.

The Journal of pharmacy and pharmacology

Zhang X,Yang X,Zhang S,Wang J,Wang M,Ma T,Wan M,Lv X,Yan T,Jia Y

Fri Apr 07 00:00:00 UTC 2023

Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.

Neurochemical research

Wu Z,Tang W,Ibrahim FEEM,Chen X,Yan H,Tao C,Wang Z,Guo Y,Fu Y,Wang Q,Ge Y

Fri Sep 01 00:00:00 UTC 2023

Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.

Neurochemical research

Wu Z,Tang W,Ibrahim FEEM,Chen X,Yan H,Tao C,Wang Z,Guo Y,Fu Y,Wang Q,Ge Y

Fri Sep 01 00:00:00 UTC 2023

Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.

Cellular immunology

Wen J,Xuan B,Gao Y,Liu Y,Wang L,He L,Meng X,Zhou T,Tao Y,Guo K,Wang Y

Wed Mar 01 00:00:00 UTC 2023

Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Journal of orthopaedic surgery and research

Niu Q,Chen H,Ou Q,Yang S,Peng Y,Xie Y,Yu L,Cheng Z,Cao Y,Wang Y

Fri Jun 02 00:00:00 UTC 2023

Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Journal of orthopaedic surgery and research

Niu Q,Chen H,Ou Q,Yang S,Peng Y,Xie Y,Yu L,Cheng Z,Cao Y,Wang Y

Fri Jun 02 00:00:00 UTC 2023

Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Journal of orthopaedic surgery and research

Niu Q,Chen H,Ou Q,Yang S,Peng Y,Xie Y,Yu L,Cheng Z,Cao Y,Wang Y

Fri Jun 02 00:00:00 UTC 2023

Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy.

Journal of orthopaedic surgery and research

Niu Q,Chen H,Ou Q,Yang S,Peng Y,Xie Y,Yu L,Cheng Z,Cao Y,Wang Y

Fri Jun 02 00:00:00 UTC 2023

Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair.

Materials today. Bio

Tao J,Yang P,Gao M,Zhang F,Wu Y,Jiang Y,Ning Y,Li Z,Ai F

Thu Jun 01 00:00:00 UTC 2023

Human umbilical cord mesenchymal stem cell-derived exosomes promote murine skin wound healing by neutrophil and macrophage modulations revealed by single-cell RNA sequencing.

Frontiers in immunology

Liu Y,Zhang M,Liao Y,Chen H,Su D,Tao Y,Li J,Luo K,Wu L,Zhang X,Yang R

Mon Apr 03 00:00:00 UTC 2023

Three-dimensional cellular visualization in mouse apical periodontitis using combined whole-mount staining and optical tissue clearing.

Journal of oral biosciences

Tazawa K,Sasaki H

Wed Mar 01 00:00:00 UTC 2023

Three-dimensional cellular visualization in mouse apical periodontitis using combined whole-mount staining and optical tissue clearing.

Journal of oral biosciences

Tazawa K,Sasaki H

Wed Mar 01 00:00:00 UTC 2023

Realizing Highly Efficient Sonodynamic Bactericidal Capability through the Phonon-Electron Coupling Effect Using Two-Dimensional Catalytic Planar Defects.

Advanced materials (Deerfield Beach, Fla.)

Mao C,Jin W,Xiang Y,Zhu Y,Wu J,Liu X,Wu S,Zheng Y,Cheung KMC,Yeung KWK

Wed Mar 01 00:00:00 UTC 2023

Activation of glucagon-like peptide-1 receptor in microglia exerts protective effects against sepsis-induced encephalopathy via attenuating endoplasmic reticulum stress-associated inflammation and apoptosis in a mouse model of sepsis.

Experimental neurology

Yi H,Duan Y,Song R,Zhou Y,Cui Y,Liu C,Mao Z,Hu J,Zhou F

Mon May 01 00:00:00 UTC 2023

Porcine Reproductive and Respiratory Syndrome Virus Modulates the Switch of Macrophage Polarization from M1 to M2 by Upregulating MoDC-Released sCD83.

Viruses

Gong X,Ma T,Zhang Q,Wang Y,Song C,Lai M,Zhang C,Fang X,Chen X

Fri Mar 17 00:00:00 UTC 2023

Betulinic Acid Inhibits the Stemness of Gastric Cancer Cells by Regulating the GRP78-TGF-β1 Signaling Pathway and Macrophage Polarization.

Molecules (Basel, Switzerland)

Chen JL,Tai YS,Tsai HY,Hsieh CY,Chen CL,Liu CJ,Wu DC,Huang YB,Lin MW

Sat Feb 11 00:00:00 UTC 2023

Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis.

Journal of nanobiotechnology

Yang N,Li M,Wu L,Song Y,Yu S,Wan Y,Cheng W,Yang B,Mou X,Yu H,Zheng J,Li X,Yu X

Fri Jan 13 00:00:00 UTC 2023

Ursolic acid promotes microglial polarization toward the M2 phenotype via PPARγ regulation of MMP2 transcription.

Neurotoxicology

Wang Y,Qiu L,Deng S,Liu F,He Z,Li M,Wang Y

Mon May 01 00:00:00 UTC 2023

Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Sheng R,Liu J,Zhang W,Luo Y,Chen Z,Chi J,Mo Q,Wang M,Sun Y,Liu C,Zhang Y,Zhu Y,Kuang B,Yan C,Liu H,Backman LJ,Chen J

Thu Jun 01 00:00:00 UTC 2023

SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.

European journal of pharmacology

Chen R,Zhang Y,Zhang H,Zhou H,Tong W,Wu Y,Ma M,Chen Y

Wed Jul 05 00:00:00 UTC 2023

SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury.

European journal of pharmacology

Chen R,Zhang Y,Zhang H,Zhou H,Tong W,Wu Y,Ma M,Chen Y

Wed Jul 05 00:00:00 UTC 2023

Berberine mitigates intracerebral hemorrhage-induced neuroinflammation in a gut microbiota-dependent manner in mice.

Aging

Liu J,Chen H,Yu T,Fu X,Qian C,Feng X

Fri Apr 07 00:00:00 UTC 2023

MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.

Molecular medicine reports

Gu C,Chen M,Li X,Geng D,Wang C

Thu Jun 01 00:00:00 UTC 2023

MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain.

Molecular medicine reports

Gu C,Chen M,Li X,Geng D,Wang C

Thu Jun 01 00:00:00 UTC 2023

Mollugin ameliorates murine allergic airway inflammation by inhibiting Th2 response and M2 macrophage activation.

European journal of pharmacology

Li X,Hou R,Ding H,Gao X,Wei Z,Qi T,Fang L

Fri May 05 00:00:00 UTC 2023

Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism.

Cellular signalling

Tian J,Zhang L,La X,Fan X,Li A,Wu C,An Y,Yan S,Dong X,Wu H,Li Z

Tue Aug 01 00:00:00 UTC 2023

Interleukin-10 genetically modified clinical-grade mesenchymal stromal cells markedly reinforced functional recovery after spinal cord injury via directing alternative activation of macrophages.

Cellular & molecular biology letters

Gao T,Huang F,Wang W,Xie Y,Wang B

Thu Mar 17 00:00:00 UTC 2022

A multifunctional drug consisting of tetracycline conjugated with odanacatib for efficient periodontitis therapy.

Frontiers in pharmacology

Li D,Zhang W,Ye W,Liu Y,Li Y,Wang Y,Shi B,Zheng X,An Y,Ma Z,Hu K,Zhou H,Xue Y

Fri Nov 18 00:00:00 UTC 2022

Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Zhang L,Zhang X,Liu Y,Wang S,Jia G

Thu Sep 01 00:00:00 UTC 2022

Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling.

iScience

Liu P,Li Y,Li M,Zhou H,Zhang H,Zhang Y,Xu J,Xu Y,Zhang J,Xia B,Cheng H,Ke Y,Zhang X

Fri Mar 18 00:00:00 UTC 2022

Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI.

Cell death discovery

Li N,Chen J,Geng C,Wang X,Wang Y,Sun N,Wang P,Han L,Li Z,Fan H,Hou S,Gong Y

Mon Feb 28 00:00:00 UTC 2022

Maresin 1 enhances osteogenic potential of mesenchymal stem cells by modulating macrophage peroxisome proliferator-activated receptor-γ-mediated inflammation resolution.

Biomaterials advances

Yao D,Zou Y,Lv Y

Sat Oct 01 00:00:00 UTC 2022

Maresin 1 enhances osteogenic potential of mesenchymal stem cells by modulating macrophage peroxisome proliferator-activated receptor-γ-mediated inflammation resolution.

Biomaterials advances

Yao D,Zou Y,Lv Y

Sat Oct 01 00:00:00 UTC 2022

One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.

Advanced healthcare materials

Guo S,Yao M,Zhang D,He Y,Chang R,Ren Y,Guan F

Tue Feb 01 00:00:00 UTC 2022

Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.

Biochemical pharmacology

Yang W,Tao K,Zhang P,Chen X,Sun X,Li R

Sat Jan 01 00:00:00 UTC 2022

Maresin 1 protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting macrophage pyroptosis and inflammatory response.

Biochemical pharmacology

Yang W,Tao K,Zhang P,Chen X,Sun X,Li R

Sat Jan 01 00:00:00 UTC 2022

Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury.

Journal of controlled release : official journal of the Controlled Release Society

Zhao R,Wang L,Wang T,Xian P,Wang H,Long Q

Sun May 01 00:00:00 UTC 2022

C1q inhibits differentiation of oligodendrocyte progenitor cells via Wnt/β-catenin signaling activation in a cuprizone-induced mouse model of multiple sclerosis.

Experimental neurology

Gao Z,Zhang C,Feng Z,Liu Z,Yang Y,Yang K,Chen L,Yao R

Tue Feb 01 00:00:00 UTC 2022

MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.

Stem cell research & therapy

Zhang Y,Le X,Zheng S,Zhang K,He J,Liu M,Tu C,Rao W,Du H,Ouyang Y,Li C,Wu D

Wed Apr 27 00:00:00 UTC 2022

Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.

International journal of pharmaceutics

Chen P,Tang S,Gao H,Zhang H,Chen C,Fang Z,Peng G,Weng H,Chen A,Zhang C,Qiu Z,Li S,Chen J,Chen L,Chen X

Mon Jul 25 00:00:00 UTC 2022

Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury.

Neural regeneration research

Wen L,Wang YD,Shen DF,Zheng PD,Tu MD,You WD,Zhu YR,Wang H,Feng JF,Yang XF

Thu Dec 01 00:00:00 UTC 2022

Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury.

Neural regeneration research

Wen L,Wang YD,Shen DF,Zheng PD,Tu MD,You WD,Zhu YR,Wang H,Feng JF,Yang XF

Thu Dec 01 00:00:00 UTC 2022

Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.

Photodiagnosis and photodynamic therapy

Li L,Yang Y,Yang Z,Zheng M,Luo G,He W,Yin R

Wed Jun 01 00:00:00 UTC 2022

Evaluation of an ImmunoPET Tracer for IL-12 in a Preclinical Model of Inflammatory Immune Responses.

Frontiers in immunology

Viola NT,Glassbrook JE,Kalluri JR,Hackett JB,Wicker MN,Sternberg J,Gibson HM

Thu Jun 02 00:00:00 UTC 2022

Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.

Pediatric research

Yang L,Yu X,Zhang Y,Liu N,Xue X,Fu J

Thu Dec 01 00:00:00 UTC 2022

Structural damage to the rat eye following long-term simulated weightlessness.

Experimental eye research

Li S,Song Q,Wu B,Kan G,Wang F,Yang J,Zhu S

Sat Oct 01 00:00:00 UTC 2022

Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.

Biochemical and biophysical research communications

Zhou Y,Chai H,Hu Y,Liu R,Jiang H,Fan R,Chen W,Chen X,Huang F

Sat Dec 17 00:00:00 UTC 2022

Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.

Bioscience reports

Cai ZH,Tian YG,Li JZ,Zhao P,Li JS,Mei X,Bai YP

Fri Oct 28 00:00:00 UTC 2022

Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.

Bioscience reports

Cai ZH,Tian YG,Li JZ,Zhao P,Li JS,Mei X,Bai YP

Fri Oct 28 00:00:00 UTC 2022

Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.

Bioscience reports

Cai ZH,Tian YG,Li JZ,Zhao P,Li JS,Mei X,Bai YP

Fri Oct 28 00:00:00 UTC 2022

Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals.

Bioscience reports

Cai ZH,Tian YG,Li JZ,Zhao P,Li JS,Mei X,Bai YP

Fri Oct 28 00:00:00 UTC 2022

An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice.

Antioxidants (Basel, Switzerland)

Olivares-González L,Velasco S,Gallego I,Esteban-Medina M,Puras G,Loucera C,Martínez-Romero A,Peña-Chilet M,Pedraz JL,Rodrigo R

Fri Dec 30 00:00:00 UTC 2022

Implantation of a nerve protector embedded with human GMSC-derived Schwann-like cells accelerates regeneration of crush-injured rat sciatic nerves.

Stem cell research & therapy

Zhang Q,Burrell JC,Zeng J,Motiwala FI,Shi S,Cullen DK,Le AD

Mon Jun 20 00:00:00 UTC 2022

Protective effects of budesonide on LPS-induced podocyte injury by modulating macrophage M1/M2 polarization: Evidence from in vitro and in silico studies.

Experimental and therapeutic medicine

Zhang X,Wang G,Shen D,Feng Y,Zhang Y,Zhang C,Li Y,Liao H

Thu Sep 01 00:00:00 UTC 2022

Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.

Biochemical pharmacology

Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F

Tue Mar 01 00:00:00 UTC 2022

Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.

Evidence-based complementary and alternative medicine : eCAM

Li Z,Ma D,Wang Y,Wu S,Wang L,Jiang Y,Zhang Y,Li X

Sun May 01 00:00:00 UTC 2022

Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.

Evidence-based complementary and alternative medicine : eCAM

Li Z,Ma D,Wang Y,Wu S,Wang L,Jiang Y,Zhang Y,Li X

Sun May 01 00:00:00 UTC 2022

Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.

International journal of biological macromolecules

Zhang D,Chang R,Ren Y,He Y,Guo S,Guan F,Yao M

Mon Oct 31 00:00:00 UTC 2022

Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.

Redox biology

Wang G,Li X,Li N,Wang X,He S,Li W,Fan W,Li R,Liu J,Hou S

Wed Jun 01 00:00:00 UTC 2022

Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.

Molecules (Basel, Switzerland)

Li B,Ji Y,Yi C,Wang X,Liu C,Wang C,Lu X,Xu X,Wang X

Wed Jun 29 00:00:00 UTC 2022

Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.

Parasites & vectors

Cui L,Wang Y,Ren L,Li Z,Jiang Y,Wang C,Liu X,Ren Y,Hu X

Tue Dec 13 00:00:00 UTC 2022

Urea transporter B downregulates polyamines levels in melanoma B16 cells via p53 activation.

Biochimica et biophysica acta. Molecular cell research

Li J,Sun Y,Yan R,Wu X,Zou H,Meng Y

Sun May 01 00:00:00 UTC 2022

In Vitro Immunomodulatory Effects of Inonotus obliquus Extracts on Resting M0 Macrophages and LPS-Induced M1 Macrophages.

Evidence-based complementary and alternative medicine : eCAM

Shen D,Feng Y,Zhang X,Liu J,Gong L,Liao H,Li R

Sat Jul 16 00:00:00 UTC 2022

Mechanical stress protects against chondrocyte pyroptosis through lipoxin A₄ via synovial macrophage M2 subtype polarization in an osteoarthritis model.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Shen P,Jia S,Wang Y,Zhou X,Zhang D,Jin Z,Wang Z,Liu D,Bai L,Yang Y

Thu Sep 01 00:00:00 UTC 2022

Progranulin deficiency promotes persistent neuroinflammation and causes regional pathology in the hippocampus following traumatic brain injury.

Glia

Zheng X,Mi T,Wang R,Zhang Z,Li W,Zhao J,Yang P,Xia H,Mao Q

Fri Jul 01 00:00:00 UTC 2022

Progranulin deficiency promotes persistent neuroinflammation and causes regional pathology in the hippocampus following traumatic brain injury.

Glia

Zheng X,Mi T,Wang R,Zhang Z,Li W,Zhao J,Yang P,Xia H,Mao Q

Fri Jul 01 00:00:00 UTC 2022

GABA regulates IL-1β production in macrophages.

Cell reports

Fu J,Han Z,Wu Z,Xia Y,Yang G,Yin Y,Ren W

Tue Dec 06 00:00:00 UTC 2022

Prognostic Value and Biological Function of Galectins in Malignant Glioma.

Frontiers in oncology

Zhu H,Liu D,Cheng L,Liu J,Wang G,Li H,Zhang Y,Mi H,Zhang S,Shu K,Yu X

Sat Jul 16 00:00:00 UTC 2022

Identification of the novel prognostic biomarker, MLLT11, reveals its relationship with immune checkpoint markers in glioma.

Frontiers in oncology

Chen L,Xiong Z,Zhao H,Teng C,Liu H,Huang Q,Wanggou S,Li X

Tue Aug 30 00:00:00 UTC 2022

miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression.

Proceedings of the National Academy of Sciences of the United States of America

Ma C,He D,Tian P,Wang Y,He Y,Wu Q,Jia Z,Zhang X,Zhang P,Ying H,Jin ZB,Hu G

Tue Feb 08 00:00:00 UTC 2022

Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.

Mediators of inflammation

Liu WZ,Ma ZJ,Kang JH,Lin AX,Wang ZH,Chen HW,Guo XD,He XG,Kang XW

Tue Aug 16 00:00:00 UTC 2022

Identification and validation of a 17-gene signature to improve the survival prediction of gliomas.

Frontiers in immunology

Tong S,Xia M,Xu Y,Sun Q,Ye L,Cai J,Ye Z,Tian D

Tue Oct 18 00:00:00 UTC 2022

Identification and validation of a 17-gene signature to improve the survival prediction of gliomas.

Frontiers in immunology

Tong S,Xia M,Xu Y,Sun Q,Ye L,Cai J,Ye Z,Tian D

Tue Oct 18 00:00:00 UTC 2022

The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.

Cells

Fu HY,Xu JM,Ai X,Dang FT,Tan X,Yu HY,Feng J,Yang WX,Ma HT,Tu RF,Gupta AK,Manandhar LK,Bao WM,Tang YM

Sat Nov 26 00:00:00 UTC 2022

Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.

Frontiers in pharmacology

Li L,Deng S,Liu M,Yang M,Li J,Liu T,Zhang T,Zhao Y,He M,Wu D,Xu Y

Fri Dec 02 00:00:00 UTC 2022

Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.

Materials today. Bio

Wang L,Zhang D,Ren Y,Guo S,Li J,Ma S,Yao M,Guan F

Sat Jan 01 00:00:00 UTC 2022

Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.

Journal of agricultural and food chemistry

Wang J,Zhang G,Yang Y,Zhang X,Shi K,Zhang X,Yan T,Jia Y

Wed Nov 09 00:00:00 UTC 2022

Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.

Clinical science (London, England : 1979)

Liang L,Liu L,Zhou W,Yang C,Mai G,Li H,Chen Y

Fri Feb 25 00:00:00 UTC 2022

Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway.

Clinical science (London, England : 1979)

Liang L,Liu L,Zhou W,Yang C,Mai G,Li H,Chen Y

Fri Feb 25 00:00:00 UTC 2022

OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression.

Cancer immunology, immunotherapy : CII

Yang S,Zhang J,Xu Y,Wang J,Zhao H,Lei J,Zhou Y,Chen Y,Wu L,Zhou M,Zheng L,Ji X,Li Y

Tue Nov 01 00:00:00 UTC 2022

Inhibition of Mer exacerbates early brain injury by regulating microglia/macrophage phenotype after subarachnoid hemorrhage in mice.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Tan X,Zheng Y,Zeng H,Peng Y,Yu X,Cao S

Thu Sep 01 00:00:00 UTC 2022

A cell-free difunctional demineralized bone matrix scaffold enhances the recruitment and osteogenesis of mesenchymal stem cells by promoting inflammation resolution.

Biomaterials advances

Yao D,Lv Y

Mon Aug 01 00:00:00 UTC 2022

A cell-free difunctional demineralized bone matrix scaffold enhances the recruitment and osteogenesis of mesenchymal stem cells by promoting inflammation resolution.

Biomaterials advances

Yao D,Lv Y

Mon Aug 01 00:00:00 UTC 2022

Mesenchymal Stem Cells Improve Cognitive Impairment and Reduce Aβ Deposition via Promoting AQP4 Polarity and Relieving Neuroinflammation in Rats With Chronic Hypertension-Induced Cerebral Small-Vessel Disease.

Frontiers in aging neuroscience

Liu XL,Ouyang FB,Hu LT,Sun P,Yang J,Sun YJ,Liao MS,Lan LF,Pei Z,Fan YH

Sat Jul 16 00:00:00 UTC 2022

Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.

Redox biology

Li H,Zhu J,Xu YW,Mou FF,Shan XL,Wang QL,Liu BN,Ning K,Liu JJ,Wang YC,Mi JX,Wei X,Shao SJ,Cui GH,Lu R,Guo HD

Mon Aug 01 00:00:00 UTC 2022

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.

International journal of molecular medicine

Wang Y,Xie W,Feng Y,Xu Z,He Y,Xiong Y,Chen L,Li X,Liu J,Liu G,Wu Q

Fri Jul 01 00:00:00 UTC 2022

Biomimetic manganese-eumelanin nanocomposites for combined hyperthermia-immunotherapy against prostate cancer.

Journal of nanobiotechnology

Liu Y,Shang W,Liu H,Hui H,Wu J,Zhang W,Gao P,Guo K,Guo Y,Tian J

Mon Jan 24 00:00:00 UTC 2022

Macrophage Extracellular Traps Exacerbate Secondary Spinal Cord Injury by Modulating Macrophage/Microglia Polarization via LL37/P2X7R/NF-κB Signaling Pathway.

Oxidative medicine and cellular longevity

Zhang C,Guo D,Qiao H,Li J,Li J,Yang Y,Chang S,Li F,Wang D,Li H,He X,Wang F

Tue Dec 06 00:00:00 UTC 2022

TRIM21 aggravates cardiac injury after myocardial infarction by promoting M1 macrophage polarization.

Frontiers in immunology

Li Z,Liu X,Zhang X,Zhang W,Gong M,Qin X,Luo J,Fang Y,Liu B,Wei Y

Tue Nov 29 00:00:00 UTC 2022

TRIM21 aggravates cardiac injury after myocardial infarction by promoting M1 macrophage polarization.

Frontiers in immunology

Li Z,Liu X,Zhang X,Zhang W,Gong M,Qin X,Luo J,Fang Y,Liu B,Wei Y

Tue Nov 29 00:00:00 UTC 2022

CXCR3 antagonist AMG487 ameliorates experimental autoimmune prostatitis by diminishing Th1 cell differentiation and inhibiting macrophage M1 phenotypic activation.

The Prostate

Hua X,Zhang J,Ge S,Liu H,Du H,Niu Q,Chen X,Yang C,Zhang L,Liang C

Thu Sep 01 00:00:00 UTC 2022

Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.

Frontiers in oncology

Yu H,Bai Y,Qiu J,He X,Xiong J,Dai Q,Wang X,Li Y,Sheng H,Xin R,Jiang L,Li Q,Li D,Zhang H,Zhang L,Chen Q,Peng J,Hu X,Zhang K

Wed Dec 15 00:00:00 UTC 2021

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization.

Investigative ophthalmology & visual science

Zhou Y,Zeng J,Tu Y,Li L,Du S,Zhu L,Cang X,Lu J,Zhu M,Liu X

Mon Mar 01 00:00:00 UTC 2021

The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer.

Journal of oncology

Zhu Q,Yuan J,He Y,Hu Y

Wed Apr 27 00:00:00 UTC 2022

Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice.

Cardiovascular therapeutics

Zhang J,Huang F,Chen L,Li G,Lei W,Zhao J,Liao Y,Li Y,Li C,Chen M

Wed Jul 21 00:00:00 UTC 2021

Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice.

Cardiovascular therapeutics

Zhang J,Huang F,Chen L,Li G,Lei W,Zhao J,Liao Y,Li Y,Li C,Chen M

Wed Jul 21 00:00:00 UTC 2021

Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.

Experimental biology and medicine (Maywood, N.J.)

Yuan X,Luo C,Wu J,Li W,Guo X,Li S,Wang B,Sun H,Tang L

Wed Sep 01 00:00:00 UTC 2021

Abdominal paracentesis drainage attenuates intestinal mucosal barrier damage through macrophage polarization in severe acute pancreatitis.

Experimental biology and medicine (Maywood, N.J.)

Yuan X,Luo C,Wu J,Li W,Guo X,Li S,Wang B,Sun H,Tang L

Wed Sep 01 00:00:00 UTC 2021

PLXNA2 knockdown promotes M2 microglia polarization through mTOR/STAT3 signaling to improve functional recovery in rats after cerebral ischemia/reperfusion injury.

Experimental neurology

Li S,Hua X,Zheng M,Wu J,Ma Z,Xing X,Ma J,Zhang J,Shan C,Xu J

Wed Dec 01 00:00:00 UTC 2021

Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.

Frontiers in cardiovascular medicine

Pan G,Liao M,Dai Y,Li Y,Yan X,Mai W,Liu J,Liao Y,Qiu Z,Zhou Z

Tue Jan 04 00:00:00 UTC 2022

Caloric restriction ameliorates high-fat diet induced cognitive deficits through attenuating neuroinflammation via the TREM2-PI3K/AKT signaling pathway.

Food & function

Wang R,Zhou Z,Wang D,Zhao Q,Zhang C,Liu C,Zhao H,Yuan C,Yuan D,Wang T

Wed Jul 21 00:00:00 UTC 2021

The glycolysis inhibitor 2-deoxyglucose ameliorates adjuvant-induced arthritis by regulating macrophage polarization in an AMPK-dependent manner.

Molecular immunology

Cai W,Cheng J,Zong S,Yu Y,Wang Y,Song Y,He R,Yuan S,Chen T,Hu M,Pan Y,Ma R,Liu H,Wei F

Wed Dec 01 00:00:00 UTC 2021

The glycolysis inhibitor 2-deoxyglucose ameliorates adjuvant-induced arthritis by regulating macrophage polarization in an AMPK-dependent manner.

Molecular immunology

Cai W,Cheng J,Zong S,Yu Y,Wang Y,Song Y,He R,Yuan S,Chen T,Hu M,Pan Y,Ma R,Liu H,Wei F

Wed Dec 01 00:00:00 UTC 2021

A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis.

eLife

Li J,Qin X,Shi J,Wang X,Li T,Xu M,Chen X,Zhao Y,Han J,Piao Y,Zhang W,Qu P,Wang L,Xiang R,Shi Y

Fri Jun 11 00:00:00 UTC 2021

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice.

Translational stroke research

Fu X,Zeng H,Zhao J,Zhou G,Zhou H,Zhuang J,Xu C,Li J,Peng Y,Cao Y,Li Y,Chen H,Wang L,Yan F,Chen G

Wed Dec 01 00:00:00 UTC 2021

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice.

Translational stroke research

Fu X,Zeng H,Zhao J,Zhou G,Zhou H,Zhuang J,Xu C,Li J,Peng Y,Cao Y,Li Y,Chen H,Wang L,Yan F,Chen G

Wed Dec 01 00:00:00 UTC 2021

Myeloid TBK1 Deficiency Induces Motor Deficits and Axon Degeneration Through Inflammatory Cell Infiltration.

Molecular neurobiology

Duan W,Yi L,Tian Y,Huang HP,Li Z,Bi Y,Guo M,Li Y,Liu Y,Ma Y,Song X,Liu Y,Li C

Sat May 01 00:00:00 UTC 2021

Myeloid TBK1 Deficiency Induces Motor Deficits and Axon Degeneration Through Inflammatory Cell Infiltration.

Molecular neurobiology

Duan W,Yi L,Tian Y,Huang HP,Li Z,Bi Y,Guo M,Li Y,Liu Y,Ma Y,Song X,Liu Y,Li C

Sat May 01 00:00:00 UTC 2021

Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation.

Journal of agricultural and food chemistry

Sheng K,Xu Y,Kong X,Wang J,Zha X,Wang Y

Wed Dec 15 00:00:00 UTC 2021

FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.

Biochemical and biophysical research communications

Liu H,Wang M,Jin Z,Sun D,Zhu T,Liu X,Tan X,Shi G

Fri Dec 10 00:00:00 UTC 2021

Simvastatin Enhances Muscle Regeneration Through Autophagic Defect-Mediated Inflammation and mTOR Activation in G93ASOD1 Mice.

Molecular neurobiology

Wang Y,Bai L,Li S,Wen Y,Liu Q,Li R,Liu Y

Thu Apr 01 00:00:00 UTC 2021

Intracellular Sphingosine-1-Phosphate Receptor 3 Contributes to Lung Tumor Cell Proliferation.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Terlizzi M,Colarusso C,Ferraro G,Monti MC,Rosa I,Somma P,Salvi R,Pinto A,Sorrentino R

Fri Sep 03 00:00:00 UTC 2021

Matrix stiffness regulates bone repair by modulating 12-lipoxygenase-mediated early inflammation.

Materials science & engineering. C, Materials for biological applications

Yao D,Qiao F,Song C,Lv Y

Wed Sep 01 00:00:00 UTC 2021

Matrix stiffness regulates bone repair by modulating 12-lipoxygenase-mediated early inflammation.

Materials science & engineering. C, Materials for biological applications

Yao D,Qiao F,Song C,Lv Y

Wed Sep 01 00:00:00 UTC 2021

Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.

Frontiers in cell and developmental biology

Bai C,Wang H,Dong D,Li T,Yu Z,Guo J,Zhou W,Li D,Yan R,Wang L,Wang Z,Li Y,Ren L

Wed Apr 21 00:00:00 UTC 2021

Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis.

Theranostics

Pan T,Zhou Q,Miao K,Zhang L,Wu G,Yu J,Xu Y,Xiong W,Li Y,Wang Y

Thu Jul 22 00:00:00 UTC 2021

The Protective Role of Yin-Yang 1 in Cardiac Injury and Remodeling After Myocardial Infarction.

Journal of the American Heart Association

Huang Y,Li L,Chen H,Liao Q,Yang X,Yang D,Xia X,Wang H,Wang WE,Chen L,Zeng C

Tue Nov 02 00:00:00 UTC 2021

Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage.

Neuroscience bulletin

Xu C,Chen H,Zhou S,Sun C,Xia X,Peng Y,Zhuang J,Fu X,Zeng H,Zhou H,Cao Y,Yu Q,Li Y,Hu L,Zhou G,Yan F,Chen G,Li J

Fri Oct 01 00:00:00 UTC 2021

Pharmacological Activation of RXR-α Promotes Hematoma Absorption via a PPAR-γ-dependent Pathway After Intracerebral Hemorrhage.

Neuroscience bulletin

Xu C,Chen H,Zhou S,Sun C,Xia X,Peng Y,Zhuang J,Fu X,Zeng H,Zhou H,Cao Y,Yu Q,Li Y,Hu L,Zhou G,Yan F,Chen G,Li J

Fri Oct 01 00:00:00 UTC 2021

Amniotic fluid-derived multipotent stromal cells drive diabetic wound healing through modulation of macrophages.

Journal of translational medicine

Subhan BS,Kwong J,Kuhn JF,Monas A,Sharma S,Rabbani PS

Wed Jan 06 00:00:00 UTC 2021

Metformin Alleviates Neuroinflammation Following Intracerebral Hemorrhage in Mice by Regulating Microglia/Macrophage Phenotype in a Gut Microbiota-Dependent Manner.

Frontiers in cellular neuroscience

Yu X,Fu X,Wu X,Tang W,Xu L,Hu L,Xu C,Zhou H,Zhou G,Li J,Cao S,Liu J,Yan F,Wang L,Liu F,Chen G

Sat Feb 05 00:00:00 UTC 2022

Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.

Frontiers in aging neuroscience

Yang XB,Zu HB,Zhao YF,Yao K

Tue Feb 15 00:00:00 UTC 2022

Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation.

International immunopharmacology

Zhang J,Wang C,Wang H,Li X,Xu J,Yu K

Tue Jun 01 00:00:00 UTC 2021

Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.

Frontiers in immunology

Manigat LC,Granade ME,Taori S,Miller CA,Vass LR,Zhong XP,Harris TE,Purow BW

Fri Jan 07 00:00:00 UTC 2022

PAK1 Silencing Attenuated Proinflammatory Macrophage Activation and Foam Cell Formation by Increasing PPARγ Expression.

Oxidative medicine and cellular longevity

Cheng WL,Zhang Q,Li B,Cao JL,Jiao L,Chao SP,Lu Z,Zhao F

Mon Jan 31 00:00:00 UTC 2022

The Impact of β-1,4-Galactosyltransferase V on Microglial Function.

Frontiers in cellular neuroscience

Wang X,Shi N,Hui M,Jin H,Gao S,Zhou Q,Zhang L,Yan M,Shen H

Tue Sep 21 00:00:00 UTC 2021

Distinct phenotypic expression levels of macrophages in neonatal lungs.

Experimental and therapeutic medicine

Fang SY,Chen JL,Chiu MH,Huang CC,Lin MW,Lam CF

Thu Apr 01 00:00:00 UTC 2021

Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice.

Journal of agricultural and food chemistry

Ma L,Ni L,Yang T,Mao P,Huang X,Luo Y,Jiang Z,Hu L,Zhao Y,Fu Z,Ni Y

Wed Feb 17 00:00:00 UTC 2021

Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.

Pharmaceutical biology

Pi XJ,Zhao QQ,Wang JX,Zhang XL,Yuan D,Hu SS,He YM,Zhang CC,Zhou ZY,Wang T

Wed Dec 01 00:00:00 UTC 2021

PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway.

Frontiers in immunology

Kong F,Sun K,Zhu J,Li F,Lin F,Sun X,Luo X,Ren C,Lu L,Zhao S,Sun J,Wang Y,Shi J

Mon Nov 01 00:00:00 UTC 2021

PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway.

Frontiers in immunology

Kong F,Sun K,Zhu J,Li F,Lin F,Sun X,Luo X,Ren C,Lu L,Zhao S,Sun J,Wang Y,Shi J

Mon Nov 01 00:00:00 UTC 2021

MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function.

Frontiers in medicine

Yan W,Shen Y,Huang J,Lu L,Zhang Q

Tue Dec 07 00:00:00 UTC 2021

A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.

Frontiers in cellular neuroscience

Liu Z,Zhu Z,He Y,Kang Q,Li F,Zhang W,He Y,Lin Y,Huang B,Mo M,Xu P,Zhu X

Tue Dec 21 00:00:00 UTC 2021

A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.

Frontiers in cellular neuroscience

Liu Z,Zhu Z,He Y,Kang Q,Li F,Zhang W,He Y,Lin Y,Huang B,Mo M,Xu P,Zhu X

Tue Dec 21 00:00:00 UTC 2021

Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes.

Journal of neuroinflammation

Fu X,Zhou G,Wu X,Xu C,Zhou H,Zhuang J,Peng Y,Cao Y,Zeng H,Li Y,Li J,Gao L,Chen G,Wang L,Yan F

Mon Aug 23 00:00:00 UTC 2021

LncRNA LINC01088 inhibits the function of trophoblast cells, activates the MAPK-signaling pathway and associates with recurrent pregnancy loss.

Molecular human reproduction

Zhao H,Li Y,Dong N,Zhang L,Chen X,Mao H,Al-Ameri SAA,Wang X,Wang Q,Du L,Wang C,Mao H

Sat Aug 07 00:00:00 UTC 2021

Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.

International immunopharmacology

Zhao P,Cai Z,Tian Y,Li J,Li K,Li M,Bai Y,Li J

Wed Dec 01 00:00:00 UTC 2021

Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.

International immunopharmacology

Zhao P,Cai Z,Tian Y,Li J,Li K,Li M,Bai Y,Li J

Wed Dec 01 00:00:00 UTC 2021

Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu H,Cai Z,Wang F,Hong L,Deng L,Zhong J,Wang Z,Cui W

Wed Sep 01 00:00:00 UTC 2021

Colon-Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu H,Cai Z,Wang F,Hong L,Deng L,Zhong J,Wang Z,Cui W

Wed Sep 01 00:00:00 UTC 2021

Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice.

Pharmaceutical biology

Wang Q,Liu L,Guan H,Zhou Y,Li Q

Wed Dec 01 00:00:00 UTC 2021

lncRNA Gm16410 Mediates PM₂.₅-Induced Macrophage Activation via PI3K/AKT Pathway.

Frontiers in cell and developmental biology

Xu J,Xu H,Ma K,Wang Y,Niu B,Zhang L,Li F

Sat Apr 03 00:00:00 UTC 2021

M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.

Journal of Crohn's & colitis

Deng F,Yan J,Lu J,Luo M,Xia P,Liu S,Wang X,Zhi F,Liu D

Tue Apr 06 00:00:00 UTC 2021

Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.

Life sciences

Fang M,Wan W,Li Q,Wan W,Long Y,Liu H,Yang X

Thu Jul 15 00:00:00 UTC 2021

Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.

Journal of neuroinflammation

Ma X,Qin C,Chen M,Yu HH,Chu YH,Chen TJ,Bosco DB,Wu LJ,Bu BT,Wang W,Tian DS

Wed Sep 15 00:00:00 UTC 2021

Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.

Journal of neuroinflammation

Ma X,Qin C,Chen M,Yu HH,Chu YH,Chen TJ,Bosco DB,Wu LJ,Bu BT,Wang W,Tian DS

Wed Sep 15 00:00:00 UTC 2021

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation.

Frontiers in immunology

Horiuchi H,Parajuli B,Komiya H,Ogawa Y,Jin S,Takahashi K,Azuma YT,Tanaka F,Suzumura A,Takeuchi H

Tue Jun 29 00:00:00 UTC 2021

Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.

Biochemical and biophysical research communications

Zhang L,Liu Y,Wang S,Long L,Zang Q,Ma J,Yu L,Jia G

Fri Nov 05 00:00:00 UTC 2021

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer.

EMBO molecular medicine

Lu W,Yu W,He J,Liu W,Yang J,Lin X,Zhang Y,Wang X,Jiang W,Luo J,Zhang Q,Yang H,Peng S,Yi Z,Ren S,Chen J,Siwko S,Nussinov R,Cheng F,Zhang H,Liu M

Mon Jan 11 00:00:00 UTC 2021

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer.

EMBO molecular medicine

Lu W,Yu W,He J,Liu W,Yang J,Lin X,Zhang Y,Wang X,Jiang W,Luo J,Zhang Q,Yang H,Peng S,Yi Z,Ren S,Chen J,Siwko S,Nussinov R,Cheng F,Zhang H,Liu M

Mon Jan 11 00:00:00 UTC 2021

Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.

International immunopharmacology

Cheng J,Hao J,Jiang X,Ji J,Wu T,Chen X,Zhang F

Fri Oct 01 00:00:00 UTC 2021

Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.

International immunopharmacology

Cheng J,Hao J,Jiang X,Ji J,Wu T,Chen X,Zhang F

Fri Oct 01 00:00:00 UTC 2021

Myeloid NEMO deficiency promotes tumor immunosuppression partly via MCP1-CCR2 axis.

Experimental cell research

Yuanyuan L,Yakun L,Zhongyao L,Le Y,Weisong D,Moran G,Hui B,Chunyan L

Mon Feb 15 00:00:00 UTC 2021

β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.

Frontiers in immunology

Koda S,Zhang B,Zhou QY,Xu N,Li J,Liu JX,Liu M,Lv ZY,Wang JL,Shi Y,Gao S,Yu Q,Li XY,Xu YH,Chen JX,Tekengne BOT,Adzika GK,Tang RX,Sun H,Zheng KY,Yan C

Fri Feb 11 00:00:00 UTC 2022

Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.

Journal of cellular and molecular medicine

Zhao P,Zhou W,Zhang Y,Li J,Zhao Y,Pan L,Shen Z,Chen W,Hui J

Sat Feb 01 00:00:00 UTC 2020

Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.

Journal of cellular and molecular medicine

Zhao P,Zhou W,Zhang Y,Li J,Zhao Y,Pan L,Shen Z,Chen W,Hui J

Sat Feb 01 00:00:00 UTC 2020

Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer.

Cancer immunology research

Qin J,Zhang X,Tan B,Zhang S,Yin C,Xue Q,Zhang Z,Ren H,Chen J,Liu M,Qian M,Du B

Sun Nov 01 00:00:00 UTC 2020

An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs.

Science translational medicine

Li WJ,Zhu XJ,Yuan TJ,Wang ZY,Bian ZQ,Jing HS,Shi X,Chen CY,Fu GB,Huang WJ,Shi YP,Liu Q,Zeng M,Zhang HD,Wu HP,Yu WF,Zhai B,Yan HX

Wed Jul 08 00:00:00 UTC 2020

Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway.

Molecular and cellular endocrinology

Han X,Ma W,Zhu Y,Sun X,Liu N

Thu Aug 20 00:00:00 UTC 2020

Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway.

Molecular and cellular endocrinology

Han X,Ma W,Zhu Y,Sun X,Liu N

Thu Aug 20 00:00:00 UTC 2020

Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.

Journal of cellular physiology

Zhang S,Zhang H,Jin Z,Wang S,Wang Y,Zhu L,Sun W,Yan B

Tue Sep 01 00:00:00 UTC 2020

Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.

Frontiers in immunology

Li Y,Zhai P,Zheng Y,Zhang J,Kellum JA,Peng Z

Tue Apr 06 00:00:00 UTC 2021

Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.

Toxicology and applied pharmacology

Ma Z,Lu Y,Yang F,Li S,He X,Gao Y,Zhang G,Ren E,Wang Y,Kang X

Sun Apr 19 00:00:00 UTC 2020

An injectable recombinant human milk fat globule-epidermal growth factor 8-loaded copolymer system for spinal cord injury reduces inflammation through NF-κB and neuronal cell death.

Cytotherapy

Gong Z,Wang C,Ni L,Ying L,Shu J,Wang J,Yu C,Xia K,Cheng F,Shi K,Xu G,Yu Q,Shen J,Chen Q,Li F,Liang C

Wed Apr 01 00:00:00 UTC 2020

Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.

Laboratory investigation; a journal of technical methods and pathology

Kong H,Wang H,Zhuo Z,Li Z,Tian P,Wu J,Liu J,Chen Z,Zhang J,Luo Q

Tue Sep 01 00:00:00 UTC 2020

AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization.

Theranostics

Yang X,Liu H,Ye T,Duan C,Lv P,Wu X,Liu J,Jiang K,Lu H,Yang H,Xia D,Peng E,Chen Z,Tang K,Ye Z

Tue Jun 01 00:00:00 UTC 2021

Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.

Journal of agricultural and food chemistry

Zhang N,Liu C,Jin L,Zhang R,Wang T,Wang Q,Chen J,Yang F,Siebert HC,Zheng X

Wed Oct 07 00:00:00 UTC 2020

TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.

Cell proliferation

Wang Y,Zhang H,Chen Q,Jiao F,Shi C,Pei M,Lv J,Zhang H,Wang L,Gong Z

Mon Jun 01 00:00:00 UTC 2020

The effect of combining Endostar with radiotherapy on blood vessels, tumor-associated macrophages, and T cells in brain metastases of Lewis lung cancer.

Translational lung cancer research

Peng L,Wang Y,Fei S,Wei C,Tong F,Wu G,Ma H,Dong X

Mon Jun 01 00:00:00 UTC 2020

Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery.

Frontiers in molecular neuroscience

Zhao S,Xiao P,Cui H,Gong P,Lin C,Chen F,Tang Z

Mon Sep 28 00:00:00 UTC 2020

Relationship of tumour-associated macrophages with poor prognosis in Wilms' tumour.

Journal of pediatric urology

Tian K,Wang X,Wu Y,Wu X,Du G,Liu W,Wu R

Mon Jun 01 00:00:00 UTC 2020

Disease Stage-Associated Alterations in Learning and Memory through the Electroacupuncture Modulation of the Cortical Microglial M1/M2 Polarization in Mice with Alzheimer's Disease.

Neural plasticity

Li L,Li L,Zhang J,Huang S,Liu W,Wang Z,Liang S,Tao J,Chen L

Tue Aug 03 00:00:00 UTC 2021

Analysis of Cyclooxygenase 2, Programmed Cell Death Ligand 1, and Arginase 1 Expression in Human Pituitary Adenoma.

World neurosurgery

Zhao G,Chen W,He J,Cui C,Zhao L,Zhao Y,Sun C,Nie D,Jin F,Kong L

Tue Dec 01 00:00:00 UTC 2020

MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.

ACS chemical neuroscience

Ma S,Wang Y,Zhou X,Li Z,Zhang Z,Wang Y,Huang T,Zhang Y,Shi J,Guan F

Wed Sep 02 00:00:00 UTC 2020

SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α.

Molecular metabolism

Zhang W,Dong Z,Xu M,Zhang S,Liu C,Chen S

Sat Feb 01 00:00:00 UTC 2020

Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.

Parkinson's disease

Feng CW,Chen NF,Chan TF,Chen WF

Tue Jan 19 00:00:00 UTC 2021

Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.

Molecular metabolism

Riedel EO,Hinrichs A,Kemter E,Dahlhoff M,Backman M,Rathkolb B,Prehn C,Adamski J,Renner S,Blutke A,de Angelis MH,Bidlingmaier M,Schopohl J,Arnold GJ,Fröhlich T,Wolf E

Mon Jun 01 00:00:00 UTC 2020

Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.

Translational stroke research

Zong X,Dong Y,Li Y,Yang L,Li Y,Yang B,Tucker L,Zhao N,Brann DW,Yan X,Hu S,Zhang Q

Mon Jun 01 00:00:00 UTC 2020

Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway.

International immunopharmacology

Yu Y,Cai W,Zhou J,Lu H,Wang Y,Song Y,He R,Pei F,Wang X,Zhang R,Liu H,Wei F

Thu Oct 01 00:00:00 UTC 2020

Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway.

International immunopharmacology

Yu Y,Cai W,Zhou J,Lu H,Wang Y,Song Y,He R,Pei F,Wang X,Zhang R,Liu H,Wei F

Thu Oct 01 00:00:00 UTC 2020

Alternatively activated macrophages are associated with the α2AP production that occurs with the development of dermal fibrosis : The role of alternatively activated macrophages on the development of fibrosis.

Arthritis research & therapy

Kanno Y,Shu E,Niwa H,Kanoh H,Seishima M

Fri Apr 10 00:00:00 UTC 2020

Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis.

Theranostics

Liu H,Yang X,Tang K,Ye T,Duan C,Lv P,Yan L,Wu X,Chen Z,Liu J,Deng Y,Zeng G,Xing J,Ye Z,Xu H

Mon May 03 00:00:00 UTC 2021

Keratinocyte-Macrophage Crosstalk by the Nrf2/Ccl2/EGF Signaling Axis Orchestrates Tissue Repair.

Cell reports

Villarreal-Ponce A,Tiruneh MW,Lee J,Guerrero-Juarez CF,Kuhn J,David JA,Dammeyer K,Mc Kell R,Kwong J,Rabbani PS,Nie Q,Ceradini DJ

Tue Nov 24 00:00:00 UTC 2020

Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.

Theranostics

Zou G,Zhang X,Wang L,Li X,Xie T,Zhao J,Yan J,Wang L,Ye H,Jiao S,Xiang R,Shi Y

Tue May 18 00:00:00 UTC 2021

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization.

Aging

Zhang J,Rong Y,Luo C,Cui W

Tue Dec 22 00:00:00 UTC 2020

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization.

Aging

Zhang J,Rong Y,Luo C,Cui W

Tue Dec 22 00:00:00 UTC 2020

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization.

Aging

Zhang J,Rong Y,Luo C,Cui W

Tue Dec 22 00:00:00 UTC 2020

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization.

Aging

Zhang J,Rong Y,Luo C,Cui W

Tue Dec 22 00:00:00 UTC 2020

A free-standing multilayer film as a novel delivery carrier of platelet lysates for potential wound-dressing applications.

Biomaterials

Tang Q,Lim T,Wei XJ,Wang QY,Xu JC,Shen LY,Zhu ZZ,Zhang CQ

Thu Oct 01 00:00:00 UTC 2020

Fusobacterium nucleatum Aggravates the Progression of Colitis by Regulating M1 Macrophage Polarization via AKT2 Pathway.

Frontiers in immunology

Liu L,Liang L,Liang H,Wang M,Lu B,Xue M,Deng J,Chen Y

Tue Oct 20 00:00:00 UTC 2020

Fusobacterium nucleatum Aggravates the Progression of Colitis by Regulating M1 Macrophage Polarization via AKT2 Pathway.

Frontiers in immunology

Liu L,Liang L,Liang H,Wang M,Lu B,Xue M,Deng J,Chen Y

Tue Oct 20 00:00:00 UTC 2020

Targeted Delivery of miRNA 155 to Tumor Associated Macrophages for Tumor Immunotherapy.

Molecular pharmaceutics

Zang X,Zhang X,Zhao X,Hu H,Qiao M,Deng Y,Chen D

Mon Apr 01 00:00:00 UTC 2019

Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59.

Cell death & disease

Zhang R,Liu Q,Peng J,Wang M,Gao X,Liao Q,Zhao Y

Mon Nov 04 00:00:00 UTC 2019

Comparative Proteomic Analysis of Murine Cutaneous Lesions Induced by Leishmania amazonensis or Leishmania major.

ACS infectious diseases

Negrão F,Giorgio S,Eberlin MN,Yates JR

Fri Aug 09 00:00:00 UTC 2019

Static Magnetic Field Accelerates Diabetic Wound Healing by Facilitating Resolution of Inflammation.

Journal of diabetes research

Shang W,Chen G,Li Y,Zhuo Y,Wang Y,Fang Z,Yu Y,Ren H

Tue Jun 09 00:00:00 UTC 2020

Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.

Frontiers in immunology

Zhang D,Ren L,Zhao M,Yang C,Liu X,Zhang H,Jiang Y,Sun X,Li T,Cui L,Hu X

Thu Oct 15 00:00:00 UTC 2020

Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway.

European journal of pharmacology

Zhou J,Yu Y,Yang X,Wang Y,Song Y,Wang Q,Chen Z,Zong S,Fan M,Meng X,Xie C,Zhou F,Liu H,Wei F

Wed Jun 05 00:00:00 UTC 2019

Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway.

European journal of pharmacology

Zhou J,Yu Y,Yang X,Wang Y,Song Y,Wang Q,Chen Z,Zong S,Fan M,Meng X,Xie C,Zhou F,Liu H,Wei F

Wed Jun 05 00:00:00 UTC 2019

Myeloid-Derived Suppressor Cells and γδT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice.

Frontiers in immunology

Zhao Y,Lu F,Ye J,Ji M,Pang Y,Wang Y,Wang L,Li G,Sun T,Li J,Ma D,Ji C

Mon Nov 16 00:00:00 UTC 2020

Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.

Journal of proteome research

Cao Y,Ding W,Zhang J,Gao Q,Yang H,Cao W,Wang Z,Fang L,Du R

Fri May 03 00:00:00 UTC 2019

Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).

Journal of autoimmunity

Liu B,Gu Y,Pei S,Peng Y,Chen J,Pham LV,Shen HY,Zhang J,Wang H

Thu Aug 01 00:00:00 UTC 2019

Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE).

Journal of autoimmunity

Liu B,Gu Y,Pei S,Peng Y,Chen J,Pham LV,Shen HY,Zhang J,Wang H

Thu Aug 01 00:00:00 UTC 2019

Toxoplasma ROP16_I/III ameliorated inflammatory bowel diseases via inducing M2 phenotype of macrophages.

World journal of gastroenterology

Xu YW,Xing RX,Zhang WH,Li L,Wu Y,Hu J,Wang C,Luo QL,Shen JL,Chen X

Sat Dec 07 00:00:00 UTC 2019

The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.

Nature communications

Ma B,Cheng H,Mu C,Geng G,Zhao T,Luo Q,Ma K,Chang R,Liu Q,Gao R,Nie J,Xie J,Han J,Chen L,Ma G,Zhu Y,Chen Q

Mon Mar 04 00:00:00 UTC 2019

Tandem Mass Tag Proteomic Analysis of in Vitro and in Vivo Models of Cutaneous Leishmaniasis Reveals Parasite-Specific and Nonspecific Modulation of Proteins in the Host.

ACS infectious diseases

Negrão F,Diedrich JK,Giorgio S,Eberlin MN,Yates JR

Fri Dec 13 00:00:00 UTC 2019

Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells.

Cellular oncology (Dordrecht)

Yin X,Han S,Song C,Zou H,Wei Z,Xu W,Ran J,Tang C,Wang Y,Cai Y,Hu Q,Han W

Thu Aug 01 00:00:00 UTC 2019

Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells.

Cellular oncology (Dordrecht)

Yin X,Han S,Song C,Zou H,Wei Z,Xu W,Ran J,Tang C,Wang Y,Cai Y,Hu Q,Han W

Thu Aug 01 00:00:00 UTC 2019

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration.

Stem cell research & therapy

Liu J,Chen B,Bao J,Zhang Y,Lei L,Yan F

Fri Nov 15 00:00:00 UTC 2019

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.

Journal of cellular and molecular medicine

Li Y,Zhou H,Li Y,Han L,Song M,Chen F,Shang G,Wang D,Wang Z,Zhang W,Zhong M

Sat Jun 01 00:00:00 UTC 2019

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.

Journal of cellular and molecular medicine

Li Y,Zhou H,Li Y,Han L,Song M,Chen F,Shang G,Wang D,Wang Z,Zhang W,Zhong M

Sat Jun 01 00:00:00 UTC 2019

Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.

Frontiers in immunology

Huang Y,He J,Liang H,Hu K,Jiang S,Yang L,Mei S,Zhu X,Yu J,Kijlstra A,Yang P,Hou S

Wed Nov 20 00:00:00 UTC 2019

Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.

Frontiers in immunology

Huang Y,He J,Liang H,Hu K,Jiang S,Yang L,Mei S,Zhu X,Yu J,Kijlstra A,Yang P,Hou S

Wed Nov 20 00:00:00 UTC 2019

Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying in Murine Model.

Frontiers in immunology

Liu L,Jin M,Tao Q,Yu L,Du J,Wang C,Luo Q,Xing T,Xu Y,Shen J,Chu D

Wed Nov 20 00:00:00 UTC 2019

Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying in Murine Model.

Frontiers in immunology

Liu L,Jin M,Tao Q,Yu L,Du J,Wang C,Luo Q,Xing T,Xu Y,Shen J,Chu D

Wed Nov 20 00:00:00 UTC 2019

Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.

Experimental neurology

Yang L,Tucker D,Dong Y,Wu C,Lu Y,Li Y,Zhang J,Liu TC,Zhang Q

Mon Jan 01 00:00:00 UTC 2018

Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.

Experimental neurology

Yang L,Tucker D,Dong Y,Wu C,Lu Y,Li Y,Zhang J,Liu TC,Zhang Q

Mon Jan 01 00:00:00 UTC 2018

l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L

Tue May 01 00:00:00 UTC 2018

l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L

Tue May 01 00:00:00 UTC 2018

ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.

Experimental cell research

Li Y,Xie Y,Hao J,Liu J,Ning Y,Tang Q,Ma M,Zhou H,Guan S,Zhou Q,Lv X

Sun Jul 15 00:00:00 UTC 2018

ER-localized protein-Herpud1 is a new mediator of IL-4-induced macrophage polarization and migration.

Experimental cell research

Li Y,Xie Y,Hao J,Liu J,Ning Y,Tang Q,Ma M,Zhou H,Guan S,Zhou Q,Lv X

Sun Jul 15 00:00:00 UTC 2018

S100A8/A9 induces microglia activation and promotes the apoptosis of oligodendrocyte precursor cells by activating the NF-κB signaling pathway.

Brain research bulletin

Wu M,Xu L,Wang Y,Zhou N,Zhen F,Zhang Y,Qu X,Fan H,Liu S,Chen Y,Yao R

Mon Oct 01 00:00:00 UTC 2018

S100A8/A9 induces microglia activation and promotes the apoptosis of oligodendrocyte precursor cells by activating the NF-κB signaling pathway.

Brain research bulletin

Wu M,Xu L,Wang Y,Zhou N,Zhen F,Zhang Y,Qu X,Fan H,Liu S,Chen Y,Yao R

Mon Oct 01 00:00:00 UTC 2018

Interleukin-33 Protects Ischemic Brain Injury by Regulating Specific Microglial Activities.

Neuroscience

Luo Q,Fan Y,Lin L,Wei J,Li Z,Li Y,Nakae S,Lin W,Chen Q

Fri Aug 10 00:00:00 UTC 2018

Interleukin-33 Protects Ischemic Brain Injury by Regulating Specific Microglial Activities.

Neuroscience

Luo Q,Fan Y,Lin L,Wei J,Li Z,Li Y,Nakae S,Lin W,Chen Q

Fri Aug 10 00:00:00 UTC 2018

Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.

BioMed research international

Sun RZ,Fan Y,Liang X,Gong TT,Wang Q,Liu H,Shan ZY,Lei L

Wed Apr 24 00:00:00 UTC 2019

Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.

BioMed research international

Sun RZ,Fan Y,Liang X,Gong TT,Wang Q,Liu H,Shan ZY,Lei L

Wed Apr 24 00:00:00 UTC 2019

Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.

Frontiers in cellular neuroscience

Su WJ,Zhang T,Jiang CL,Wang W

Wed Sep 30 00:00:00 UTC 2020

Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus.

Frontiers in cellular neuroscience

Su WJ,Zhang T,Jiang CL,Wang W

Wed Sep 30 00:00:00 UTC 2020

The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang Q,Lv C,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B

Tue Sep 04 00:00:00 UTC 2018

The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Wang Q,Lv C,Sun Y,Han X,Wang S,Mao Z,Xin Y,Zhang B

Tue Sep 04 00:00:00 UTC 2018

Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.

Frontiers in cellular neuroscience

Zhang B,Wei YZ,Wang GQ,Li DD,Shi JS,Zhang F

Thu Oct 01 00:00:00 UTC 2020

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.

Biochimica et biophysica acta. Molecular basis of disease

Bichell TJV,Wegrzynowicz M,Tipps KG,Bradley EM,Uhouse MA,Bryan M,Horning K,Fisher N,Dudek K,Halbesma T,Umashanker P,Stubbs AD,Holt HK,Kwakye GF,Tidball AM,Colbran RJ,Aschner M,Neely MD,Di Pardo A,Maglione V,Osmand A,Bowman AB

Thu Jun 01 00:00:00 UTC 2017

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.

Biochimica et biophysica acta. Molecular basis of disease

Thu Jun 01 00:00:00 UTC 2017

GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.

Cellular signalling

Zhang L,Li Z,Ding G,La X,Yang P,Li Z

Fri Sep 01 00:00:00 UTC 2017

GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.

Cellular signalling

Zhang L,Li Z,Ding G,La X,Yang P,Li Z

Fri Sep 01 00:00:00 UTC 2017

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.

Journal of Alzheimer's disease : JAD

Lu Y,Dong Y,Tucker D,Wang R,Ahmed ME,Brann D,Zhang Q

Fri Feb 23 00:00:00 UTC 2018

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.

Journal of Alzheimer's disease : JAD

Lu Y,Dong Y,Tucker D,Wang R,Ahmed ME,Brann D,Zhang Q

Fri Feb 23 00:00:00 UTC 2018

Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.

Neuroscience letters

Zhang ML,Zhang XJ,Kang J,Zhang HJ,Chen XL,Liu N,Liu SQ,Ma WD,Zhang GX,Zhu L

Wed May 10 00:00:00 UTC 2017

Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.

Neuroscience letters

Zhang ML,Zhang XJ,Kang J,Zhang HJ,Chen XL,Liu N,Liu SQ,Ma WD,Zhang GX,Zhu L

Wed May 10 00:00:00 UTC 2017

A(H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice.

Brain, behavior, and immunity

Qi F,Yang J,Xia Y,Yuan Q,Guo K,Zou J,Yao Z

Tue Mar 01 00:00:00 UTC 2016

A(H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice.

Brain, behavior, and immunity

Qi F,Yang J,Xia Y,Yuan Q,Guo K,Zou J,Yao Z

Tue Mar 01 00:00:00 UTC 2016

Autophagic flux regulates microglial phenotype according to the time of oxygen-glucose deprivation/reperfusion.

International immunopharmacology

Xia CY,Zhang S,Chu SF,Wang ZZ,Song XY,Zuo W,Gao Y,Yang PF,Chen NH

Sat Oct 01 00:00:00 UTC 2016

Autophagic flux regulates microglial phenotype according to the time of oxygen-glucose deprivation/reperfusion.

International immunopharmacology

Xia CY,Zhang S,Chu SF,Wang ZZ,Song XY,Zuo W,Gao Y,Yang PF,Chen NH

Sat Oct 01 00:00:00 UTC 2016

Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)

Shimojima C,Takeuchi H,Jin S,Parajuli B,Hattori H,Suzumura A,Hibi H,Ueda M,Yamamoto A

Sun May 15 00:00:00 UTC 2016

Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)

Shimojima C,Takeuchi H,Jin S,Parajuli B,Hattori H,Suzumura A,Hibi H,Ueda M,Yamamoto A

Sun May 15 00:00:00 UTC 2016

Neonatal BCG vaccination of mice improves neurogenesis and behavior in early life.

Brain research bulletin

Yang J,Qi F,Gu H,Zou J,Yang Y,Yuan Q,Yao Z

Fri Jan 01 00:00:00 UTC 2016

Neonatal BCG vaccination of mice improves neurogenesis and behavior in early life.

Brain research bulletin

Yang J,Qi F,Gu H,Zou J,Yang Y,Yuan Q,Yao Z

Fri Jan 01 00:00:00 UTC 2016

Effects of IL-4 on pulmonary fibrosis and the accumulation and phenotype of macrophage subpopulations following thoracic irradiation.

International journal of radiation biology

Groves AM,Johnston CJ,Misra RS,Williams JP,Finkelstein JN

Thu Dec 01 00:00:00 UTC 2016

Effects of IL-4 on pulmonary fibrosis and the accumulation and phenotype of macrophage subpopulations following thoracic irradiation.

International journal of radiation biology

Groves AM,Johnston CJ,Misra RS,Williams JP,Finkelstein JN

Thu Dec 01 00:00:00 UTC 2016

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.

Human molecular genetics

Iida M,Katsuno M,Nakatsuji H,Adachi H,Kondo N,Miyazaki Y,Tohnai G,Ikenaka K,Watanabe H,Yamamoto M,Kishida K,Sobue G

Thu Jan 15 00:00:00 UTC 2015

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.

Human molecular genetics

Iida M,Katsuno M,Nakatsuji H,Adachi H,Kondo N,Miyazaki Y,Tohnai G,Ikenaka K,Watanabe H,Yamamoto M,Kishida K,Sobue G

Thu Jan 15 00:00:00 UTC 2015

M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis.

PLoS neglected tropical diseases

Mukhopadhyay D,Mukherjee S,Roy S,Dalton JE,Kundu S,Sarkar A,Das NK,Kaye PM,Chatterjee M

Thu Oct 01 00:00:00 UTC 2015

M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis.

PLoS neglected tropical diseases

Mukhopadhyay D,Mukherjee S,Roy S,Dalton JE,Kundu S,Sarkar A,Das NK,Kaye PM,Chatterjee M

Thu Oct 01 00:00:00 UTC 2015

Ethanol supports macrophage recruitment and reinforces invasion and migration of Lewis lung carcinoma.

Alcoholism, clinical and experimental research

Yu K,Yang J,Wang F,Chen L,Lu Y,Luo J,Wang S

Wed Oct 01 00:00:00 UTC 2014

Ethanol supports macrophage recruitment and reinforces invasion and migration of Lewis lung carcinoma.

Alcoholism, clinical and experimental research

Yu K,Yang J,Wang F,Chen L,Lu Y,Luo J,Wang S

Wed Oct 01 00:00:00 UTC 2014

Ethanol supports macrophage recruitment and reinforces invasion and migration of Lewis lung carcinoma.

Alcoholism, clinical and experimental research

Yu K,Yang J,Wang F,Chen L,Lu Y,Luo J,Wang S

Wed Oct 01 00:00:00 UTC 2014

Ethanol supports macrophage recruitment and reinforces invasion and migration of Lewis lung carcinoma.

Alcoholism, clinical and experimental research

Yu K,Yang J,Wang F,Chen L,Lu Y,Luo J,Wang S

Wed Oct 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: A-I; AI type I arginase; Arginase; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase-1; Arginase1; HGNC:663; Liver Arginase; Liver-type arginase; Type 1 Arginase; Type I arginase

View more View less

Gene Aliases: AI; AI256583; Arg-1; ARG1; PGIF

View more View less

UniProt ID: (Human) P05089, (Rat) P07824, (Mouse) Q61176

View more View less

Entrez Gene ID: (Human) 383, (Rat) 29221, (Mouse) 11846

View more View less

Function(s)

arginase activity manganese ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines metal ion binding hydrolase

Process(es)

urea cycle liver development positive regulation of endothelial cell proliferation arginine catabolic process aging response to herbicide response to manganese ion response to zinc ion response to selenium ion regulation of L-arginine import response to amine arginine catabolic process to ornithine lung development collagen biosynthetic process response to vitamin A response to vitamin E response to drug response to amino acid response to cadmium ion response to axon injury response to methylmercury mammary gland involution maternal process involved in female pregnancy protein homotrimerization cellular response to hydrogen peroxide cellular response to lipopolysaccharide cellular response to interleukin-4 cellular response to glucagon stimulus cellular response to dexamethasone stimulus cellular response to transforming growth factor beta stimulus arginine metabolic process female pregnancy response to wounding response to lipopolysaccharide response to peptide hormone response to steroid hormone

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

ARG1 Polyclonal Antibody

ARG1 Antibody (16001-1-AP) in ICC/IF

Product Details

16001-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!