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Proteintech
ARHGAP4 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-16697
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARHGAP4 fusion protein Ag10091
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1000 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: VALQGRVNQL VQTLIVQPDR VFPPLTSLPG PVYEKCMAPP SASCLGDAQL ESLGADNEPE LEAEMPAQED DLEGVVEAVA CFAYTGRTAQ ELSFRRGDVL RLHERASSDW WRGEHNGMRG LIPHKYITLP AGTEKQVVGA GLQTAGESGS SPEGLLASEL VHRPEPCTSP EAMGPSGHRR RCLVPASPEQ HVEVDKAVAQ NMDSVFKELL GKTSVRQGLG PASTTSPSPG PRSPKAPPSS RLGRNKGFSR GPGAPASPSA SHPQGLDTTP KPH
Target Information
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTPase-activating protein p115; KIAA0131; p115; RG RhoGAP4; Rho GTPase-activating protein 4; Rho-GAP hematopoietic protein C1; Rho-type GTPase-activating protein 4; unnamed protein product
Gene Aliases: A130009C12Rik; A530015A20Rik; ARHGAP4; C1; KIAA0131; mKIAA0131; p115; RGC1; RHOGAP4; SrGAP4
UniProt ID: (Human) P98171
Entrez Gene ID: (Human) 393, (Mouse) 171207
cytoskeleton organization
signal transduction
Rho protein signal transduction
nervous system development
negative regulation of fibroblast migration
negative regulation of cell migration
negative regulation of axon extension
regulation of small GTPase mediated signal transduction
regulation of synapse assembly
positive regulation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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