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Bethyl Laboratories
ARHGDIB/D4-GDI/RhoGDI2 Polyclonal Antibody
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FIGURE: 1 / 3
ARHGDIB/D4-GDI/RhoGDI2 Antibody (A304-815A) in IHC (P)
Detection of human ARHGDIB/D4-GDI by immunohistochemistry. Sample: FFPE section of human breast carcinoma inflammatory cell infiltrate. Antibody: Affinity purified rabbit anti-ARHGDIB/D4-GDI (Product # A304-815A) (Lot 2) used at a dilution of 1:5,000 0.2 µg/mL.
Product Details
A304-815A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 50 to 100 of human Rho GDP dissociation inhibitor (GDI) beta.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta
Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
UniProt ID: (Human) P52566
Entrez Gene ID: (Human) 397
movement of cell or subcellular component
negative regulation of cell adhesion
multicellular organism development
regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
cellular response to redox state
negative regulation of trophoblast cell migration
regulation of actin cytoskeleton reorganization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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