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Proteintech
ARHGEF10 Polyclonal Antibody
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Product Details
11112-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARHGEF10 Fusion Protein Ag1605 (342-641 aa encoded by BC036809)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YLNKLLSSG SRYLIRSDDM IETVYNDRGE IVKTKERRVF MLNDVLMCAT VSSRPSHDSR VMSSQRYLLK WSVPLGHVDA IEYGSSAGTG EHSRHLAVHP PESLAVVANA KPNKVYMGPG QLYQDLQNLL HDLNVIGQIT QLIGNLKGNY QNLNQSVAHD WTSGLQRLIL KKEDEIRAAD CCRIQLQLPG KQDKSGRPTF FTAVFNTFTP AIKESWVNSL QMAKLALEEN HMGWFCVEDD GNHIKKEKHP LLVGHMPVMV AKQQEFKIEC AAYNPEPYLN NESQPDSFST AHGFLWVRCV Y (342-641 aa encoded by BC036809)
Target Information
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: KIAA0294; Rho guanine nucleotide exchange factor (GEF) 10; Rho guanine nucleotide exchange factor 10
Gene Aliases: 6430549H08Rik; ARHGEF10; GEF10; KIAA0294; mKIAA0294; RGD1565043; SNCV
UniProt ID: (Human) O15013, (Mouse) Q8C033
Entrez Gene ID: (Human) 9639, (Mouse) 234094, (Rat) 306618
myelination in peripheral nervous system
actin cytoskeleton organization
positive regulation of Rho protein signal transduction
regulation of small GTPase mediated signal transduction
centrosome duplication
positive regulation of stress fiber assembly
mitotic spindle assembly
regulation of Rho protein signal transduction
activation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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