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Bethyl Laboratories
ARHGEF5 Polyclonal Antibody
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FIGURE: 1 / 2
ARHGEF5 Antibody (IHC-00652) in IHC (P)
Detection of human ARHGEF5 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-ARHGEF5 (Product # IHC-00652) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1:100.
Product Details
IHC-00652
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 600 and 650 of human Rho guanine nucleotide exchange factor (GEF) 5.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee and White-tufted-ear marmoset
Target Information
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; ephexin3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene; unnamed protein product
Gene Aliases: ARHGEF5; GEF5; P60; TIM; TIM1
UniProt ID: (Human) Q12774
Entrez Gene ID: (Human) 7984
myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
regulation of small GTPase mediated signal transduction
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
hematopoietic stem cell homeostasis
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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