The antibody detects endogenous levels of total ARID1B / BAF250B protein.
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARID domain-containing protein 1B; AT rich interactive domain 1B (SWI1-like); AT-rich interactive domain-containing protein 1B; BAF250B; BRG1-associated factor 250b; BRG1-binding protein ELD/OSA1; BRG1-binding protein hELD/OSA1; ELD (eyelid)/OSA protein; hOsa2; Osa homolog 2; p250R; transcription factor 1
Gene Aliases: 6A3-5; ARID1B; BAF250B; BRIGHT; CSS1; DAN15; ELD/OSA1; KIAA1235; MRD12; OSA2; P250R; smcf-1; Smcf1
UniProt ID: (Human) Q8TF02
Molecular Function: actin or actin-binding cytoskeletal protein