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Bethyl Laboratories
ARID4A Polyclonal Antibody
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FIGURE: 1 / 2
ARID4A Antibody (A302-231A) in WB
Detection of human ARID4A by western blot. Samples: Whole cell lysate (50 µg) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ARID4A antibody (Product # A302-231A) (lot A302-231A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A302-231A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 900 and 950 of human AT-rich interactive domain-containing protein 4A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARID domain-containing protein 4A; AT rich interactive domain 4A (RBP1-like); AT-rich interactive domain-containing protein 4A; RBBP-1; retinoblastoma binding protein 1; Retinoblastoma-binding protein 1
Gene Aliases: ARID4A; RBBP-1; RBBP1; RBP-1; RBP1
UniProt ID: (Human) P29374
Entrez Gene ID: (Human) 5926
regulation of gene expression by genetic imprinting
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
spermatogenesis
histone deacetylation
histone H4-K20 trimethylation
histone H3-K9 trimethylation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
erythrocyte development
histone H3-K4 trimethylation
establishment of Sertoli cell barrier
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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