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Invitrogen
ARID5A Polyclonal Antibody
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Product Details
PA5-32020
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ARID5A. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.55 mg/mL
Amount
155 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 3xFlag-human ARID5A-transfected 293T.
Predicted reactivity: Mouse (83%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth (Patsialou et al., 2005 [PubMed 15640446]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARID domain-containing protein 5A; AT rich interactive domain 5A (MRF1-like); AT-rich interactive domain-containing protein 5A; Modulator recognition factor 1; modulator recognition factor I; MRF-1; RFVG5814; unnamed protein product
Gene Aliases: ARID5A; MRF-1; MRF1; RP11-363D14
UniProt ID: (Human) Q03989
Entrez Gene ID: (Human) 10865
transcription regulatory region sequence-specific DNA binding
DNA binding
chromatin binding
transcription corepressor activity
RNA binding
protein binding
transcription factor binding
estrogen receptor binding
RNA stem-loop binding
mRNA 3'-UTR AU-rich region binding
identical protein binding
sequence-specific DNA binding
retinoid X receptor binding
thyroid hormone receptor binding
androgen receptor binding
negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
immune system process
regulation of transcription from RNA polymerase II promoter
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
cellular response to estrogen stimulus
positive regulation of 3'-UTR-mediated mRNA stabilization
positive regulation of T-helper 17 type immune response
positive regulation of T-helper 1 cell cytokine production
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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