Immunogen sequence: TSKYPSRDMY RESENSSFPS HRHQEKLHVN YLTSLHLQDK KSAAAEAPTD DQPTDLSLPK NPHKPTGKVL GLAHSTTGPQ ESKGISQFQV LGSQSRDCHP KACRVSPMTM SGPKKYPESL SRSGKPHHVR LENFRKME
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 24%.
MRF2 belongs to the ARID (A-T rich interaction domain) family of transcription factors. The ARID (A-T Rich Interaction Domain) is a helix-turn-helix motif-based DNA-binding domain, which is conserved in all eukaryotes and diagnostic of a family that includes fifteen distinct human proteins. It shows important roles in development, tissue-specific gene expression and proliferation control. This protein has a nonredundant function during growth and in the development of the reproductive system. MRF2 is essential for accumulation of lipid stores in postnatal life. Northern blot analysis shows expression in mouse lung, heart, small intestine, kidney, muscle, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARID domain-containing protein 5B; AT rich interactive domain 5B (MRF1-like); AT-rich interactive domain 5B (MRF1-like); AT-rich interactive domain-containing protein 5B; DESRT; Modulator recognition factor 2; modulator recognition factor 2 (MRF2); MRF-2; MRF1-like protein; MRF2; RP11-341A19.1
Gene Aliases: ARID5B; DESRT; MRF-2; MRF2
UniProt ID: (Human) Q14865
Entrez Gene ID: (Human) 84159